RNA-based therapy brings new hope for an incurable blood cancer
Three thousand new cases of Mantle Cell Lymphoma (MCL), a form of blood cancer, appear in the United States each year. With a median survival span of only five to seven years, according to the Leukemia and ...
Cancer
Oct 10, 2012 |
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Women respond better to the treatment of lymph gland cancer with antibodies than men
(Medical Xpress)—Women respond much better than men to the treatment of chronic follicular lymphoma with a monoclonal antibody that targets CD20 (rituximab). These are the findings of a multi-centre, Austria-wide ...
Cancer
Oct 10, 2012 |
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Solving puzzle of B-cell lymphoma development
Germinal centers are sites in the organs of the lymphatic system, formed during the course of an immune response to infection, where B cells intensely proliferate and modify their DNA in order to produce ...
Immunology
Sep 23, 2012 |
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Mutation ID'd in Waldenstrom's macroglobulinemia
(HealthDay)—MYD88 L265P is a common, recurring mutation in patients with Waldenström's macroglobulinemia, according to a study published in the Aug. 30 issue of the New England Journal of Medicine.
Cancer
Aug 30, 2012 |
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B cell survival holds key to chronic graft vs. host disease
Leukemia and lymphoma patients who receive life-saving stem cell or bone marrow transplants often experience chronic side effects that significantly decrease quality of life, can last a lifetime, and ultimately affect their ...
Diseases, Conditions, Syndromes
Aug 16, 2012 |
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New key element discovered in pathogenesis of Burkitt lymphoma
Burkitt lymphoma is a malignant, fast-growing tumor that originates from a subtype of white blood cells called B lymphocytes of the immune system and often affects internal organs and the central nervous system. Now Dr. Sandrine ...
Cancer
Aug 13, 2012 |
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Researchers find potential key to new treatment for mantle cell lymphoma
Researchers at Moffitt Cancer Center and colleagues have demonstrated that the inhibition of signal transducer and activator of transcription 3 (STAT3) in mouse models of mantle cell lymphoma (MCL), an aggressive and incurable ...
Cancer
Jul 18, 2012 |
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New understanding of cell metabolism provides therapeutic target
(Medical Xpress) -- One of the reasons that cancer cells proliferate is that they metabolize fuel differently from normal cells. A team led by Blossom Damania, PhD, at the University of North Carolina at Chapel Hill ...
Cancer
Jul 03, 2012 |
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New drug dramatically improves survival in Hodgkin lymphoma patients
A new cancer drug with remarkably few side effects is dramatically improving survival in Hodgkin lymphoma patients who fail other treatments and are nearly out of options.
Cancer
Jun 27, 2012 |
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'Rediscovered' lymphoma drug helps double survival: study
(HealthDay) -- A drug first developed in East Germany in the 1960s has re-emerged as a potent "new" weapon against certain types of non-Hodgkin lymphomas, researchers report.
Cancer
Jun 04, 2012 |
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New therapy on the horizon for ALK+ non-small cell lung cancer
A new compound that targets anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer is well-tolerated by patients and is already showing early signs of activity, including in patients who no longer respond to ...
Cancer
Jun 01, 2012 |
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Protein may represent a switch to turn off B cell lymphoma
Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain ...
Cancer
May 07, 2012 |
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Lymphoma therapy could deliver a double punch
B cell lymphomas are a group of cancers of that originate in lymphoid tissue from B cells, the specialized immune cell type that produces antibodies. The development of B cell lymphoma is associated with several known genetic ...
Cancer
Apr 30, 2012 |
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Study identifies trigger for alternate reproduction of HIV-related cancer virus
A research team led by Children's National Medical Center has identified a trigger that causes latent Kaposi's sarcoma-associated herpesvirus (KSHV) to rapidly replicate itself. KSHV causes Kaposi's sarcoma, primary effusion ...
Cancer
Apr 17, 2012 |
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New compound targets key mechanism behind lymphoma
Scientists at Fox Chase Cancer Center in Philadelphia have come one step closer to developing the first treatment to target a key pathway in lymphoma. The new findings will be announced at the AACR Annual Meeting 2012 on ...
Cancer
Apr 03, 2012 |
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