Keeping the human brain in a healthy state requires a delicate balance between the generation of new cellular material and the destruction of old. Specialized structures known as lysosomes, found in nearly every cell in your ...
Aug 7, 2017
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A rare and controversial mutation in the phospholipase D3 (PLD3) protein—previously linked to Alzheimer's disease—interferes with PLD3's vital recycling function inside neurons. Matthew Schrag of Vanderbilt University ...
Apr 8, 2021
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(Medical Xpress)—Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.
Mar 28, 2013
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In the field of scientific research, details matter. The minutia of processes and structures are explained with specificity, data points are reported to the most precise decimal and seeing is believing.
Feb 25, 2022
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Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for ...
Apr 2, 2012
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Garbage comes in all shapes and sizes. Cells, the body's functional units of life, also produce 'garbage' - debris and dysfunctional elements the body must get rid of. Failure to dispose of this garbage could trigger various ...
Jun 24, 2011
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The formation of amyloid plaques in the brain is a hallmark of Alzheimer's disease. But drugs designed to reduce accumulations of these plaques have so far yielded, at best, mixed results in clinical trials.
Dec 1, 2022
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After years of building hope for a treatment, Rochester researchers and clinicians will begin the first controlled clinical trial for Juvenile Batten disease this summer, thanks to $1 million in grants from the Food and Drug ...
May 31, 2011
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St. Jude Children's Research Hospital scientists have discovered how an aggressive tumor of the muscle and soft tissue hijacks an export pathway in cells to lay the groundwork for cancer progression and resistance to chemotherapy. ...
Dec 21, 2015
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Researchers from Yale University School of Medicine have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. The study, ...
Aug 7, 2017
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