An international study has shed new light on the genetic factors associated with Parkinson's disease, pointing at a group of lysosomal storage disorder genes as potential major contributors to the onset and progression of ...
Nov 14, 2017
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MIT biologists have discovered a function of a gene that is believed to account for up to 40 percent of all familial cases of amyotrophic lateral sclerosis (ALS). Studies of ALS patients have shown that an abnormally expanded ...
May 7, 2018
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Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide energy for muscle ...
Mar 13, 2013
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Across the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal lobar degeneration (FTLD), which develop when neurons in specific parts of the ...
Jul 9, 2020
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Adding to the growing body of literature demonstrating the feasibility of correcting lethal genetic diseases before birth, researchers at Children's Hospital of Philadelphia (CHOP) have used DNA base editing in a prenatal ...
Jul 13, 2021
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Researchers at Rush University Medical Center have identified a key immunological defense reaction to the metals in joint replacement devices, leading to loosening of the components and early failure.
Mar 4, 2009
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Imagine that garbage haulers don't exist. Slowly, the trash accumulates in our offices, our homes, it clogs the streets and damages our cars, causes illness and renders normal life impossible.
Aug 29, 2013
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How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo Clinic researchers studying pancreatic cancer—the third deadliest form of cancer in the U.S.—recently made a discovery that ...
Dec 18, 2023
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Researchers in South Australia have found a genetic link between Alzheimer's disease and the endo-lysosomal system, a critical part of biological recycling machinery that maintains the health of brain cells.
Aug 21, 2018
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The role played by mutations in the LRRK2 gene in promoting Parkinson's disease has long intrigued scientists, and even led to an experimental drug that inhibits the over-active protein. Yet exactly how LRRK2 triggers this ...
Jul 26, 2023
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