The immune response to infections is a delicate balance. We need just enough action to clear away the offending bacteria or viruses, but not so much that our own bodies suffer collateral damage.
Oct 15, 2020
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211
Type 1 diabetes, or T1D, is an autoimmune disease in which the body's immune cells—led by inflammatory macrophages—attack and destroy the beta cells of the pancreas that produce insulin.
Sep 9, 2020
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25
Macrophages are white blood cells that, depending on the signals they get from the immune system, become specialized in either increasing or decreasing inflammation. When macrophages are programmed to be pro-inflammatory, ...
Aug 24, 2020
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Both in the periphery and the center of lung tumors, characteristic accumulations of certain white blood cells, known as macrophages, are often found. In this case they are called tumor-associated macrophages. There are two ...
Aug 4, 2020
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Macrophages are immune cells that patrol the body looking for potential threats like viruses, bacteria, and cancer cells, and engulf and destroy them. However, cancerous tumors have a nasty trick up their sleeves: they secrete ...
Apr 29, 2020
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143
Do the insulin-producing beta cells in the pancreas unwittingly produce a signal that aids their own demise in Type 1 diabetes?
Feb 21, 2020
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104
Researchers have determined that after lungs recover from infection, alveolar macrophages (immune cells that live in the lungs and help protect the lungs against infection) are different in multiple ways and those differences ...
Jan 28, 2020
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Due to their function, the lungs are constantly exposed to various compounds carried in the air, sometimes harmful, sometimes harmless. The lung immune system plays a pivotal role in deciding or not deciding to mount an immune ...
Sep 3, 2019
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A new form of immunotherapy that has so far been tested on mice makes it probable that oncologists in the future may be able to treat some of the patients who are not responding to existing types of immunotherapy. Instead ...
Aug 27, 2019
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In recent years it has been increasingly appreciated that immune cells within the tumor microenvironment contribute to tumor progression and, importantly, to the tumor's response to therapy. To better understand the specific ...
Aug 26, 2019
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