Immunology
A Trojan horse? Immune cells ferry deadly fungus from mouse lung into the blood
A report today in PLOS Pathogens shows how inhaled fungal spores exit the lung and trigger a fatal infection in mice.
Jun 27, 2019
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News tagged with macrophage cells
Oncology & Cancer
Scientists track brain tumor turncoats with advanced imaging
Glioblastomas, the deadliest type of brain tumor in adults, attract "turncoats." These are macrophages, a type of immune cell, which promote tumor progression and mask tumors from the immune system's scrutiny. To better understand ...
Jun 25, 2019
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Arthritis & Rheumatism
Preventing cell death as novel therapeutic strategy for rheumatoid arthritis
A collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that death of macrophages, an immune cell type, can trigger the disease. Moreover, they discovered how the ...
May 14, 2019
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Arthritis & Rheumatism
Researchers advance understandings of the cellular mechanisms driving rheumatoid arthritis
Newly identified subsets of cell types present in joint tissue in people with rheumatoid arthritis and how they interact may explain why only some people respond to existing medications, according to two studies by co-senior ...
May 9, 2019
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HIV & AIDS
New angle of attack drives cellular HIV-reservoirs to self-destruction
While current therapies for HIV can successfully manage active infection, the virus can survive in tissue reservoirs, including macrophage cells, and remain a persistent problem. Now, Dr. David Russell, William Kaplan Professor ...
Mar 25, 2019
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Medical research
Modified immune cells issue alert when detecting cancer in mice
Stanford scientists were able to engineer immune cells known as macrophages to detect and flag cancer in mice. The researchers hope the technique can be used for early cancer diagnostics in humans.
Mar 19, 2019
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Immunology
Scientists stumble upon a model to study a lethal complication
More and more hospitalized patients with sepsis are being diagnosed with a deadly complication characterized by high levels of inflammation. A team of Yale researchers has uncovered clues to the cause of this complication—which ...
Feb 11, 2019
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Medical research
Researchers breathe new life into COPD research using mouse models
The airways and lungs are affected by a range of diseases, but while some have been well characterized and treated, others, such as chronic obstructive pulmonary disorder (COPD), are still somewhat of an enigma. This condition ...
Feb 1, 2019
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Immunology
Energizing the immune system to eat cancer
Immune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. Now researchers at the Abramson Cancer Center of the University of Pennsylvania say they've identified how ...
Jan 21, 2019
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Cardiology
Macrophage cells key to helping heart repair—and potentially regenerate, new study finds
Scientists at the Peter Munk Cardiac Centre have identified the type of cell key to helping the heart repair and potentially regenerate following a heart attack.
Dec 11, 2018
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