Oncology & Cancer
Cancer stem cells trigger macrophage aging in mouse study
Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.
Nov 14, 2023
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News tagged with macrophages
Oncology & Cancer
Study finds senescent immune cells promote lung tumor growth
Macrophages are a type of white blood cell that are among the body's first line of defense against infection. In addition to killing harmful microorganisms, macrophages typically can initiate a response against tumors. However, ...
Sep 26, 2023
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Medical research
Unveiling dynamics of human macrophage specification during prenatal development
Researchers led by Prof. Li Hanjie from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences have unveiled the dynamics of human macrophage specification across 19 different tissues from ...
Sep 12, 2023
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Biomedical technology
Study sheds light on why wounds often heal poorly in diabetics
When tiny particles called exosomes, which shuttle signals between cells, are defective in diabetic patients, they can drive inflammation and impair healing of wounds, according to a new Nano Today study led by University ...
Sep 8, 2023
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Immunology
Study shows microRNAs in immune cells help protect against metabolic defects in obesity
Vanderbilt researchers have demonstrated that a cluster of microRNAs—small pieces of RNA that regulate gene expression—work in a type of immune cells called macrophages to help protect against metabolic defects in obesity.
Sep 8, 2023
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Medical research
Training immune cells to remove 'trash' helps resolve lung inflammation
Inflammation is a standard part of our bodies' immune system response. But sometimes this response becomes hyperactivated in our lungs, causing inflammation to continue unchecked, which can be fatal. Many deaths from COVID-19 ...
Aug 24, 2023
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Oncology & Cancer
Researcher discusses how lung macrophages evolve during metastatic growth of lung colonies in a mouse model of melanoma
A new editorial paper titled "A macrophage is a macrophage is a macrophage—in metastasis" has been published in Oncotarget.
Aug 23, 2023
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Genetics
New study sheds light on the molecular mechanisms underlying SLC29A3 disorders
In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies). This gene encodes for the lysosomal protein that transport ...
Aug 22, 2023
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Cardiology
Red blood cell particles reduce fat deposition in arteries, potentially treating atherosclerosis
Atherosclerosis is a disease in which fat, cholesterol, and other substances build up inside artery walls. This can lead to plaque formation, which can block arteries and cause heart attacks and strokes. Immune cells play ...
Aug 10, 2023
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Immunology
Spatial dimension of macrophage heterogeneity in liver diseases
The hepatic immune landscape is a dynamic compartment, notably composed of highly heterogeneous and adapting myeloid cells. Liver resident macrophage distribution across the tissue and bone-marrow derived monocyte accumulation ...
Aug 8, 2023
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