Diseases, Conditions, Syndromes

Blocking how the malaria parasite suppresses the immune response

The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.

Diseases, Conditions, Syndromes

Investigational malaria vaccine gives strong, lasting protection

Two U.S. Phase 1 clinical trials of a novel candidate malaria vaccine have found that the regimen conferred unprecedentedly high levels of durable protection when volunteers were later exposed to disease-causing malaria parasites. ...

Diseases, Conditions, Syndromes

Microscopic CCTV reveals secrets of malaria invasion

State-of-the-art video microscopy has enabled researchers at WEHI, Australia, to see the molecular details of how malaria parasites invade red blood cells—a key step in the disease.

Diseases, Conditions, Syndromes

Hidden malaria life cycle discovered in the spleen

Groundbreaking studies published today in the New England Journal of Medicine and PLOS Medicine have found large numbers of malaria parasites hiding in the human spleen where they actively multiply in a previously unrecognized ...

Medications

Scientists design new drug compound to stop malaria in its tracks

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop ...

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