A hijacking of healthy cellular circuits
Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...
Cancer
Apr 08, 2013 |
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KDM1 may represent a new therapeutic target for glioma
Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...
Cancer
Apr 08, 2013 |
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Researchers discover brain cancer treatment using genetic material from bone marrow cells
In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers at Henry Ford Hospital have discovered a novel approach for treatment of ...
Cancer
Apr 01, 2013 |
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Immortality gene mutation identifies brain tumors, other cancers
Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...
Cancer
Mar 18, 2013 |
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Study identifies growth factor essential to the most common malignant pediatric brain tumor
A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...
Cancer
Feb 28, 2013 |
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'Chemo brain': Study finds fog-like condition related to chemotherapy's effect on new brain cells and rhythms
(Medical Xpress)—It's not unusual for cancer patients being treated with chemotherapy to complain about not being able to think clearly, connect thoughts or concentrate on daily tasks. The complaint – ...
Neuroscience
Feb 21, 2013 |
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Corticorelin acetate has steroid-sparing effect in brain cancer
(HealthDay)—Corticorelin acetate (CrA) administration to patients with peritumoral brain edema (PBE) allows the reduction of steroid doses and is associated with reduced incidence and severity of steroid-induced ...
Cancer
Feb 06, 2013 |
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Researchers identify enzyme involved in deadly brain tumors
One of the most common types of brain tumors in adults, glioblastoma multiforme, is one of the most devastating. Even with recent advances in surgery, radiation and chemotherapy, the aggressive and invasive tumors become ...
Cancer
Jan 17, 2013 |
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New biomarker may help in detecting gliomas
Researchers using sophisticated genetic testing techniques have identified a promising new biomarker for diagnosis of glioma—the most common type of malignant brain tumor, reports the January issue of Neurosurgery, official journal of the Congres ...
Cancer
Jan 16, 2013 |
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MicroRNA-218 targets medulloblastoma, most aggressive childhood brain cancer
Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the expression of faulty genes ...
Cancer
Dec 13, 2012 |
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Research shows immune system response is detrimental to novel brain cancer therapy
For the first time, researchers have demonstrated that the response of natural killer (NK) cells is detrimental to glioblastoma virotherapy, a novel way of treating malignant brain cancer by injecting a virus into the tumor. ...
Cancer
Dec 04, 2012 |
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Using unique combination of diet and radiation therapy, researchers successfully destroy brain tumor cells
A team of brain cancer researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has effectively treated brain tumor cells using a unique combination of diet and radiation therapy. The study, ...
Cancer
Dec 04, 2012 |
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Uninsured brain cancer patients may be more likely than insured to die after surgery to remove tumor
Uninsured patients who undergo surgery to remove a brain tumor could be twice as likely to die in the hospital as those who have the same operation but are privately insured, new Johns Hopkins research suggests. In teaching ...
Surgery
Nov 19, 2012 |
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For brain tumors, origins matter
(Medical Xpress)—Since stem cells and progenitor cells are regulated by different growth factors, brain tumors arising from these cells might respond differently to different therapies. Researchers at Sanford-Burnham ...
Cancer
Nov 13, 2012 |
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Intracranial tumors can be resected safely in elderly
(HealthDay)—Elderly patients do not have poorer short-term outcomes after surgical resection of primary or metastatic intracranial tumors, after accounting for other risk factors, according to research ...
Cancer
Oct 21, 2012 |
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