Oncology & Cancer

A thought-provoking new therapeutic target for brain cancer?

Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant ...

Oncology & Cancer

Genetics of melanoma chemoresistance

Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In a new paper, Ohanna et al. reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") ...

Oncology & Cancer

Glioblastoma multiforme in the Dock

Glioblastoma multiforme (GBM) is the most common malignant brain cancer in humans. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. ...

Oncology & Cancer

Disabling enzyme reduces tumor growth, cripples cancer cells

Knocking out a single enzyme dramatically cripples the ability of aggressive cancer cells to spread and grow tumors, offering a promising new target in the development of cancer treatments, according to a new study by researchers ...

Medical research

Epigenetic drugs in the mission to beat rare cancers

Only one in 100,000 people suffer from a pheochromocytoma, a tumor of the adrenal gland. If the tumor has already metastasized, a radioactive compound can be used to detect malignant cells that have spread to other parts ...

Oncology & Cancer

Metabolism may keep cancer cells in check

Researchers have found that a long-known tumor suppressor, whose mechanism of holding cell growth in check has remained murky for over 40 years, works in part by keeping the cell's energy metabolism behaving in grown-up fashion.

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