News tagged with malignant tumor


Scientists find Achilles' heel of cancer cells

Several substances inhibiting so-called HDAC enzymes have been studied in trials searching for new anti-cancer drugs in recent years. "Trials have shown that HDAC inhibitors are very effective in arresting growth of cultured ...

Cancer created Nov 05, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Team finds mechanism of one of the most powerful tumor-suppressor proteins, Chd5

A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.

Cancer created Jan 10, 2013 | popularity 4.5 / 5 (6) | comments 0 | with audio podcast

DNA-repairing protein may be key to preventing recurrence of some cancers

Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...

Cancer created Jan 28, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Discovery of new vaccine approach for treatment of cancer

(Medical Xpress) -- Scientists in Trinity College Dublin, Ireland, have developed a new vaccine to treat cancer at the pre-clinical level. The research team led by Professor Kingston Mills, Professor of Experimental ...

Cancer created Dec 21, 2011 | popularity 5 / 5 (3) | comments 0

Early biomarker for pancreatic cancer identified

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently ...

Cancer created May 15, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Researchers discover breakthrough in ovarian cancer

Researchers at The University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center in Phoenix have discovered that many women with low-grade serous carcinoma of the ovary or peritoneum have seen their tumors ...

Cancer created Feb 14, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

BRAF inhibitor treatment causes melanoma cells to shift how they produce energy

A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...

Cancer created Mar 08, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Immortality gene mutation identifies brain tumors, other cancers

Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...

Cancer created Mar 18, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Promising new target for stifling the growth and spread of cancer

Cancer and chronic inflammation are partners in peril, with the latter increasing the likelihood that malignant tumors will develop, grow and spread. Researchers at the University of California, San Diego ...

Cancer created Jun 13, 2011 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Old drugs find new target for treating brain tumor

Scientists at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center, in collaboration with colleagues in Boston and South Korea, say they have identified a novel ...

Cancer created Nov 18, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

'First-in-human' drug for malignant glioma available in experimental trial

The UC Cancer Institute is one of three centers internationally approved to test an experimental drug's safety and pharmacokinetics and also assess the clinical benefit against recurrent malignant glioma, an aggressive form ...

Cancer created Feb 15, 2012 | popularity 5 / 5 (2) | comments 0

Blocking telomerase kills cancer cells but provokes resistance, progression

Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...

Cancer created Feb 21, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Outwitting a brainy gene

(Medical Xpress) -- The very first in the series of mutations causing colon cancer occurs in the beta-catenin gene; this gene is abnormally activated in about 90 percent of colorectal cancer patients, and in a much smaller ...

Cancer created May 01, 2012 | popularity 5 / 5 (2) | comments 0

DNA deletions promote cancer, collateral damage makes it vulnerable

Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that the collateral damage they inflict on neighboring genes exposes cancer cells to vul ...

Cancer created Aug 15, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Red wine ingredient resveratrol stops breast cancer growth

Cheers! A new research report appearing in the October 2011 issue of The FASEB Journal shows that resveratrol, the "healthy" ingredient in red wine, stops breast cancer cells from growing by blocking the growth effects of est ...

Cancer created Sep 29, 2011 | popularity 4 / 5 (2) | comments 1