Bisphenol A alters mammary gland development in monkeys
A new study finds that fetal exposure to the plastic additive bisphenol A, or BPA, alters mammary gland development in primates. The finding adds to the evidence that the chemical can be causing health problems in humans ...
Medical research
May 07, 2012 |
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A novel surface marker helps scientists 'fish out' mammary gland stem cells
Stem cells are different from all other cells in our body because they retain the remarkable genetic plasticity to self-renew indefinitely as well as develop into cell types with more specialized functions. However, this ...
Cancer
Apr 11, 2013 |
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His and hers: Male hormones control differences in mammary gland nerve growth
Johns Hopkins scientists have found a surprising mechanism that gives male sex hormones like testosterone control over the gender-specific absence or presence of mammary gland nerves that sense the amount ...
Medical research
Dec 06, 2012 |
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Scientists identify progenitor cells, potential new 'roots' of breast cancer
Scientists have discovered new types of early cells in mammary glands, uncovering clues to the origins of different breast cancers - and potential new drug targets, according to findings published in Breast Ca ...
Cancer
Oct 29, 2012 |
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Lactation protein suppresses tumors and metastasis in breast cancer, scientists discover
A protein that is necessary for lactation in mammals inhibits the critical cellular transition that is an early indicator of breast cancer and metastasis, according to research conducted at the University at Buffalo and Princeton ...
Cancer
Oct 24, 2012 |
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New insights on control of pituitary hormone outside of brain has implications for breast cancer
The hormone prolactin is produced by the pituitary gland in the brain and then travels via the bloodstream to cells throughout the body, where it exerts multiple reproductive and metabolic effects, most notably ...
Genetics
Oct 01, 2012 |
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Study uncovers mechanism by which tumor suppressor MIG6 triggers cell suicide
Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells—a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. ...
Cancer
Sep 24, 2012 |
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Serotonin could play a large role in bone loss
Scientists have long known that calcium leaches from the bones both during lactation and in certain types of cancer. The driver behind these phenomena is a molecule called parathyroid hormone related protein (PTHrP), which ...
Medical research
Feb 21, 2012 |
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BPA exposure in utero may increase predisposition to breast cancer
A recent study accepted for publication in Molecular Endocrinology, a journal of The Endocrine Society, found that perinatal exposure to environmentally relevant doses of bisphenol A (BPA) alters long-term hormone respon ...
Health
Oct 03, 2011 |
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Plastic chemical may expose foetuses to cancer (Update)
France said Tuesday it would call for Europe-wide controls on a paper product containing bisphenol A after a watchdog agency said the widely-used chemical may expose unborn children to breast cancer later in life.
Health
Apr 09, 2013 |
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Researchers find new clue to clinical trial failures of MMP cancer therapies
Proposed cancer therapeutic drugs based on blocking the catalytic activities of matrix metalloproteinases (MMPs), which profoundly remodel the environment surrounding a breast cell, have performed poorly ...
Cancer
Feb 12, 2013 |
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Breast milk contains more than 700 bacteria: Microbes taken from breast milk by the infant are identified
Spanish researchers have traced the bacterial microbiota map in breast milk, which is the main source of nourishment for newborns. The study has revealed a larger microbial diversity than originally thought: ...
Health
Jan 04, 2013 |
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Toasting your health: Take care with alcohol consumption
(Medical Xpress)—The holidays are a time to consume—food, gifts, and spirits. Here are a few alcohol-related story ideas from The Methodist Hospital. Because alcohol's effects on human physiology are complex, advice about ...
Health
Dec 20, 2012 |
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Changes in progenitor cell population in breast may be overlooked factor in breast cancer
The DNA mutations that accumulate over time as women age are not the sole contributor to the higher frequency of breast cancer in women over 50, Mark LaBarge, PhD, a researcher at Lawrence Berkeley National Laboratory (LBNL) ...
Cancer
Dec 17, 2012 |
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Preclinical data support ongoing clinical trials testing IDO inhibitors as a treatment for cancer
Inhibitors of indoleamine 2,3-dioxygenase (IDO) are being assessed in clinical trials as a potential treatment for recurrent or refractory solid tumors. Clear genetic rationale for these trials, together with evidence that ...
Cancer
Jul 19, 2012 |
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