Medications

Many drugs are just fine years after they 'expire,' study finds

Chances are, your medicine cabinet contains some pills that are past their expiration date. You might even have some pain relievers, some cough syrup or some sleeping pills that were purchased back when Richard Nixon was ...

Oncology & Cancer

A promising breath-test for cancer

The global quest to use a person's breath analysis for rapid, inexpensive and accurate early-stage testing for cancer and other diseases has taken a leap forward.

Neuroscience

How proteins control information processing in the brain

A complicated interaction between proteins is needed for information to pass from one nerve cell to the next. Researchers at the Martin Luther University Halle-Wittenberg (MLU) have now managed to study this process in the ...

Diseases, Conditions, Syndromes

New method for early diagnosis of liver diseases by proteomics

Two or three drinks every day could put your liver in danger. Using proteomics and machine learning, researchers now present a revolutionary tool to predict whether an individual has alcohol-related liver disease and if an ...

Diseases, Conditions, Syndromes

Combating gastroenteritis

Gastroenteritis from food borne illness is a major public health concern both in Australia and overseas, and Swinburne University of Technology researchers are working on the early detection of bacteria that significantly ...

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Mass spectrometry

Mass spectrometry (MS) is an analytical technique for the determination of the elemental composition of a sample or molecule. It is also used for elucidating the chemical structures of molecules, such as peptides and other chemical compounds. The MS principle consists of ionizing chemical compounds to generate charged molecules or molecule fragments and measurement of their mass-to-charge ratios. In a typical MS procedure:

MS instruments consist of three modules: an ion source, which can convert gas phase sample molecules into ions (or, in the case of electrospray ionization, move ions that exist in solution into the gas phase); a mass analyzer, which sorts the ions by their masses by applying electromagnetic fields; and a detector, which measures the value of an indicator quantity and thus provides data for calculating the abundances of each ion present. The technique has both qualitative and quantitative uses. These include identifying unknown compounds, determining the isotopic composition of elements in a molecule, and determining the structure of a compound by observing its fragmentation. Other uses include quantifying the amount of a compound in a sample or studying the fundamentals of gas phase ion chemistry (the chemistry of ions and neutrals in a vacuum). MS is now in very common use in analytical laboratories that study physical, chemical, or biological properties of a great variety of compounds.

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