Mast cells give clues in diagnosis, treatment of dengue
A protein produced by mast cells in the immune system may predict which people infected with dengue virus will develop life-threatening complications, according to researchers at Duke Medicine and Duke-National University ...
Diseases, Conditions, Syndromes
Apr 30, 2013 |
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Mechanism found for destruction of key allergy-inducing complexes, researchers say
Researchers have learned how a man-made molecule destroys complexes that induce allergic responses—a discovery that could lead to the development of highly potent, rapidly acting interventions for a host of acute allergic ...
Medical research
Oct 28, 2012 |
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Key immune substance linked to asthma, study finds
Stanford University School of Medicine investigators have linked a master molecule of the immune system, gamma-interferon, to the pathology of asthma, in a study of mice. This somewhat surprising finding — the key immune ...
Diseases, Conditions, Syndromes
Jul 01, 2011 |
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First comprehensive DNA study of mast cell leukemia uncovers clues that could improve therapy
Cancer researchers at Cold Spring Harbor Laboratory (CSHL) have carried out the first comprehensive study of the changes seen in the DNA of a patient with mast cell leukemia (MCL), an extremely aggressive subtype of acute ...
Cancer
Dec 16, 2011 |
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Large-scale Japanese genomics project finds eight new loci linked to atopic dermatitis
Around one in ten Japanese school children suffer from a debilitating form of eczema known as atopic dermatitis (AD). Despite clear signs that the condition is heritable, the genetic origins of the disease ...
Genetics
Feb 22, 2013 |
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Mitochondrial components are a possible trigger of auto-inflammatory illnesses
(Medical Xpress)—Many illnesses, including psoriasis, include inflammatory responses that occur without an apparent infection and worsen with stress. In a study using cultured human mast cells in vitro and in rats, researchers ...
Inflammatory disorders
Jan 02, 2013 |
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Mechanism found connecting metastatic breast cancer and arthritis
Working with mouse models, researchers have found a strong connection between autoimmune arthritis and increased aggressiveness in metastatic breast cancer. The connection appears to involve the tendency of autoimmune arthritis ...
Immunology
Apr 01, 2012 |
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Common antimicrobial inhibits immune cell function
(Medical Xpress) -- Triclosan, a common antibacterial agent found in many hand soaps and other products, is known to have the added benefit of alleviating allergic skin conditions such as eczema. In a study recently published ...
Medications
Jan 06, 2012 |
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New target discovered for food allergy treatment
Researchers at National Jewish Health have discovered a novel target for the treatment of food allergies. Erwin Gelfand, MD, and his colleagues report in the October 2012 issue of the Journal of Allergy and Clinical Immunology that l ...
Immunology
Nov 01, 2012 |
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Immune cells with a killer instinct: Tried-and-tested anti-tumour drug displays new effect
Imiquimod, a drug used to treat skin cancer, has been shown to have a previously unknown effect on immune cells. The drug transforms cells known as dendritic cells into "tumour killers" that attack the tumour ...
Immunology
Mar 26, 2012 |
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Research identifies a protein group that may kick-start allergic reactions
(Medical Xpress) -- Allergies, or hypersensitivities of the immune system, are more common than ever before. According to the Asthma and Allergies Foundation of America, one in five Americans suffers from ...
Immunology
Aug 02, 2012 |
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Study sheds light on late phase of asthma attacks
New research led by scientists from Imperial College London explains why around half of people with asthma experience a 'late phase' of symptoms several hours after exposure to allergens. The findings, published in the journal ...
Diseases, Conditions, Syndromes
Aug 13, 2011 |
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Immune cell plays dual role in allergic skin disease
(Medical Xpress) -- An immune cell involved in initiating the symptoms of an allergic skin reaction may play an equally, or perhaps more important, role in suppressing the reaction once it becomes chronic. This finding in ...
Medical research
Oct 18, 2011 |
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Mast cells have critical role in initializing pulmonary fibrosis
Pulmonary fibrosis is a chronic, deadly disease that affects five million people worldwide. It is irreversible, its cause is poorly understood, and it has a median survival of only about 3 years. A new study ...
Medical research
Apr 11, 2013 |
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FDA clears test for mastocytosis diagnosis
The Food and Drug Administration has approved a new test to help physicians diagnose a group of rare cell disorders. The test, or assay, was developed by an expert at Virginia Commonwealth University in the field of mast ...
Medical research
May 22, 2012 |
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