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Scientists decode DNA to find breast tumor signatures that predict treatment response

Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering ...

Genetics created Jun 10, 2012 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Estrogen-lowering drugs reduce mastectomy rates for breast cancer patients

In the first large trial of its kind in the United States, researchers have shown that estrogen-lowering drugs can shrink tumors and reduce mastectomy rates for patients with stage 2 or 3 breast cancer.

Cancer created May 09, 2011 | popularity 3.5 / 5 (2) | comments 0 | with audio podcast

Choosing the best breast cancer treatment option

According to published reports from the Institute of Medicine and the New England Journal of Medicine, roughly one-third of early-stage breast cancer patients undergo mastectomy even though breast conservation surgery with r ...

Cancer created Feb 20, 2012 | popularity 5 / 5 (1) | comments 0

Study: Preoperative estrogen-blocking therapy may preempt need for mastectomy

Preoperative treatment with aromatase inhibitors increases the likelihood that postmenopausal women with estrogen receptor-positive breast cancer will be able to have breast-conserving surgery rather than a mastectomy, according ...

Cancer created Mar 23, 2012 | popularity 5 / 5 (1) | comments 0

Procedure to freeze fat cells helps woman avoid more surgery

Breast cancer, a double mastectomy and kidney cancer - in all, nine surgeries in three years - left Kathleen Bindyke feeling like a battered warrior. But she decided to put herself into better shape than when the ordeal began.

Cancer created Jun 08, 2012 | popularity 5 / 5 (1) | comments 0

New classification of fat grafting techniques proposed

(HealthDay)—As the use of fat grafting in plastic surgery continues to evolve, a new way of classifying fat grafting techniques has been proposed that aims to match the technique to the specific clinical ...

Surgery created Sep 10, 2012 | popularity 5 / 5 (1) | comments 0

Nearly 170 million years of healthy life lost due to cancer in 2008

The first detailed study to estimate the global impact of cancer on the number of healthy years of life lost by patients has revealed that nearly 170 million years of healthy life were lost because of cancer in 2008, according ...

Cancer created Oct 15, 2012 | popularity 5 / 5 (1) | comments 0

What is BRCA1?

Actress Angelina Jolie has today written an op-ed in the New York Times explaining that she has opted to have a double mastectomy because she carries the hereditary BRCA1 gene, which she says increases her risk o ...

Cancer created May 15, 2013 | popularity 5 / 5 (1) | comments 2

Mastectomy

Mastectomy is the medical term for the surgical removal of one or both breasts, partially or completely. Mastectomy is usually done to treat breast cancer; in some cases, women and some men believed to be at high risk of breast cancer have the operation prophylactically, that is, to prevent cancer rather than treat it. It is also the medical procedure carried out to remove breast cancer tissue in males. Alternatively, certain patients can choose to have a wide local excision, also known as a lumpectomy, an operation in which a small volume of breast tissue containing the tumor and some surrounding healthy tissue is removed to conserve the breast. Both mastectomy and lumpectomy are what are referred to as "local therapies" for breast cancer, targeting the area of the tumor, as opposed to systemic therapies such as chemotherapy, hormonal therapy, or immunotherapy.

Traditionally, in the case of breast cancer, the whole breast was removed. Currently the decision to do the mastectomy is based on various factors including breast size, number of lesions, biologic aggressiveness of a breast cancer, the availability of adjuvant radiation, and the willingness of the patient to accept higher rates of tumor recurrences after lumpectomy and radiation. Outcome studies comparing mastectomy to lumpectomy with radiation have suggested that routine radical mastectomy surgeries will not always prevent later distant secondary tumors arising from micro-metastases prior to discovery, diagnosis, and operation.

For more information about Mastectomy, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: radiation therapy , women , breast cancer