News tagged with matrix metalloproteinase


Antibiotic studied to reduce hemorrhagic stroke damage

A new study will help determine if an antibiotic is a partial antidote for the poisonous effect blood has on the brain following a hemorrhagic stroke, researchers say.

Cardiology created Apr 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers find new clue to clinical trial failures of MMP cancer therapies

Proposed cancer therapeutic drugs based on blocking the catalytic activities of matrix metalloproteinases (MMPs), which profoundly remodel the environment surrounding a breast cell, have performed poorly ...

Cancer created Feb 12, 2013 | popularity not rated yet | comments 0

Smoking affects heart surgery outcome even a year after quitting

Smoking cessation even a year prior to coronary artery bypass grafting (CABG) surgery does not fully normalize the changes smoking has made to the saphenous (leg) veins used for the surgery and may lead to later graft failure, ...

Health created Jan 02, 2013 | popularity 5 / 5 (2) | comments 0

New mouse model of debilitating lung disease suggests potential treatment regimen

LAM, short for pulmonary lymphangioleiomyomatosis, affects about 1 in 10,000 women of childbearing age and is characterized by proliferation of smooth muscle-like cells in the lung, destruction of lung tissue, and growth ...

Medical research created Oct 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Correlates of diabetic foot complications identified

(HealthDay) -- For patients with diabetes, increased poly(ADP-ribose) (PAR) immunoreactivity, reduced abundance of type 1 procollagen, and impaired skin structure correlate with foot complications, according ...

Diabetes created Jul 08, 2012 | popularity not rated yet | comments 0

New stroke treatment could prevent and reduce brain damage

Researchers at the University of Missouri have demonstrated the effectiveness of a potential new therapy for stroke patients in an article published in the journal Molecular Neurodegeneration. Created to target a specific enzyme known to a ...

Neuroscience created Jun 11, 2012 | popularity not rated yet | comments 0 | with audio podcast

Biomarkers may predict the progression of spinal damage in patients with ankylosing spondylitis

A new study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, has identified five biomarkers that may predict the progression of structural damage in the spine of patients with ...

Arthritis & Rheumatism created Jun 06, 2012 | popularity not rated yet | comments 0

Study identifies gene critical to development and spread of lung cancer

A single gene that promotes initial development of the most common form of lung cancer and its lethal metastases has been identified by researchers at Mayo Clinic in Florida. Their study suggests other forms of cancer may ...

Cancer created Apr 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Live imaging shows response to cancer drugs can be boosted by altering tumor microenvironment

It should be possible to significantly improve the response of common cancers to existing "classical" chemotherapy drugs, say scientists at Cold Spring Harbor Laboratory (CSHL), by introducing agents that alter the interaction ...

Cancer created Apr 16, 2012 | popularity 5 / 5 (1) | comments 0

Dual mode laser therapy effectively treats acne vulgaris

(HealthDay) -- A series of Nd:YAG laser treatments effectively and rapidly reduces both inflammatory and noninflammatory acne vulgaris lesions, according to a study published in the April issue of the Journal of ...

Diseases, Conditions, Syndromes created Mar 27, 2012 | popularity not rated yet | comments 0

New synthetic molecules treat autoimmune disease in mice

A team of Weizmann Institute scientists has turned the tables on an autoimmune disease. In such diseases, including Crohn's and rheumatoid arthritis, the immune system mistakenly attacks the body's tissues. But the scientists ...

Immunology created Dec 25, 2011 | popularity 4.8 / 5 (8) | comments 0 | with audio podcast

Fibrous stroma associated with poor prognosis in lung squamous cell carcinoma

The nature of the connective tissue surrounding lung cancer nests can help predict the aggressiveness of squamous cell carcinoma, according to research published in the September issue of the Journal of Thoracic Oncology, the of ...

Cancer created Sep 01, 2011 | popularity not rated yet | comments 0