Psychology & Psychiatry

Molecular profiling of Ketamine's rapid antidepressant effect

One third of the patients with major depressive disorder suffer from treatment resistance and do not respond to commonly used antidepressants. Ketamine, a drug that works through a different mechanism, improves depressive ...

Neuroscience

MicroRNA molecule modulates behavioural response to stress

Chronic stress influences our mood and behavior. Scientists of the "Max Planck – Weizmann Laboratory for Experimental Neuropsychiatry and Behavioral Neurogenetics" investigated the molecular mechanisms of how the brain ...

Neuroscience

Learning brakes in the brain

A brain capable of learning is important for survival: only those who learn can endure in the natural world. When it learns, the brain stores new information by changing the strength of the junctions that connect its nerve ...

Neuroscience

Biochemical mechanisms of memory

A discovery by a research team led by Ryohei Yasuda at the Max Planck Florida Institute for Neuroscience has significantly advanced basic understanding of biochemical mechanisms associated with how memories are formed.

Medical research

New muscle power from the lab

(Medical Xpress)—Unlike the heart muscle, the musculature of the locomotive organs has the capacity to heal itself. What makes this possible are muscle-specific stem cells known as satellite cells. Located on the muscle ...

Oncology & Cancer

New inhibitor blocks the oncogenic protein KRAS

One of the major goals in the development of anti-cancer treatments is to find an inhibitor effective against the oncogenic protein known as KRAS. Despite decades of active agent research, efforts to intercede in this protein's ...

Medical research

Between B cells and T cells

Mature cells develop through a number of immature stages. During this process, they must remember the specialization they are committed to. For immune system B cells, Rudolf Grosschedl of the Max Planck Institute of Immunobiology ...

Cardiology

Cells make costume changes for cardiac regeneration

(Medical Xpress)—If the heart following a heart attack is not sufficiently supplied with blood, heart tissue dies. In adult humans, the ability to heal itself is hardly developed. Scientists from the Max Planck Institute ...

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