Researchers find molecular switch turning on self-renewal of liver damage
The liver is one of the few organs in our body that can regenerate itself, but how it occurs is a biological mystery. New research from BRIC, University of Copenhagen and the Finsen Laboratory, Rigshospitalet, ...
Medical research
Mar 07, 2013 |
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New approach evaluates effect of physical activity on estrogen metabolism in postmenopausal women
Researchers have generated new insights into the ways in which physical activity affects how much estrogen is broken down and secreted in the urine of postmenopausal women. These findings enhance understanding of the potential ...
Cancer
Apr 10, 2013 |
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Scientists home in on cause of osteoarthritis pain
Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could ...
Arthritis & Rheumatism
Dec 27, 2012 |
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Microbubbles improve myocardial remodelling after infarction
German scientists from the Bonn University Hospital successfully tested a method in mice allowing the morphological and functional sequelae of a myocardial infarction to be reduced. Tiny gas bubbles are made to oscillate ...
Medical research
Feb 21, 2013 |
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Cancer biology: Keeping bad company
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of ...
Cancer
Jan 16, 2013 |
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A hijacking of healthy cellular circuits
Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...
Cancer
Apr 08, 2013 |
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Smoking linked with worse urothelial cancer prognosis in patients, especially women
Smoking significantly increases individuals' risk of developing serious forms of urothelial carcinoma and a higher likelihood of dying from the disease, particularly for women. That is the conclusion of a recent study published ...
Cancer
Mar 14, 2013 |
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Research may explain why some people with schizophrenia do not respond to treatment
(Medical Xpress)—New research suggests that the molecular mechanism leading to schizophrenia may be different in patients who fail to respond to anti-psychotic medication compared to patients who do respond.
Psychology & Psychiatry
Nov 29, 2012 |
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New study finds key mechanism in calcium regulation
All living cells keep their cellular calcium concentration at a very low level. Since a small increase in calcium can affect many critical cellular functions (an elevated calcium concentration over an extended period can ...
Neuroscience
Jan 03, 2013 |
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Tiny tools help advance medical discoveries: Researchers are designing tools to analyze cells at the microscale
To understand the progression of complex diseases such as cancer, scientists have had to tease out the interactions between cells at progressively finer scales—from the behavior of a single tumor cell in ...
Medical research
Jan 08, 2013 |
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Shutting down DNA construction: How senescence halts growth of potential cancers
Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks ...
Cancer
Apr 04, 2013 |
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Meditation expertise changes experience of pain
(Medical Xpress)—Meditation can change the way a person experiences pain, according to a new study by UW–Madison neuroscientists.
Neuroscience
Nov 16, 2012 |
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Tiny RNA molecule may have role in polycystic ovary syndrome, insulin resistance
A group of tiny RNA molecules with a big role in regulating gene expression also appear to have a role in causing insulin resistance in woman with polycystic ovary syndrome and, perhaps, in all women, researchers ...
Diabetes
Mar 19, 2013 |
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Medroxyprogesterone acetate linked to immune suppression
(HealthDay)—Use of the injectable contraceptive depot medroxyprogesterone acetate (MPA), common in areas such as sub-Saharan Africa with high HIV-1 prevalence, is associated with suppression of the immune ...
Immunology
Feb 01, 2013 |
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Novel gene drives development of different types of ovarian cancer
Researchers at Mayo Clinic Cancer Center have identified a novel gene that can contribute to a woman's susceptibility for developing ovarian cancer. Researchers identified the gene, called HNF1B, through large-scale analysis ...
Cancer
Mar 27, 2013 |
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