Scientists find first human iPSC from patients with maturity onset diabetes of the young
Joslin scientists report the first generation of human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes of the young (MODY). These cells offer a powerful resource for ...
Medical research
Jan 31, 2013 |
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Beta-catenin molecule is required for tooth root formation
Today, the International and American Associations for Dental Research (IADR/AADR) published a paper titled "ß-catenin is Required in Odontoblasts for Tooth Root Formation." The paper, written by lead authors Tak-Heun Kim ...
Dentistry
Jan 23, 2013 |
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Novel technique reveals dynamics of telomere DNA structure
Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel technique to reveal structural ...
Medical research
Jan 17, 2013 |
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Enzyme CaM kinase II relaxes muscle cells: Researchers find overactive enzyme in failing hearts
A certain enzyme, the CaM kinase II, keeps the cardiac muscle flexible. By transferring phosphate groups to the giant protein titin, it relaxes the muscle cells. This is reported by researchers led by Prof. ...
Cardiology
Jan 17, 2013 |
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Cancer biology: Keeping bad company
The p53 tumor suppressor protein manages DNA repair mechanisms in response to genetic damage and kills off precancerous cells before they multiply. The loss of p53 due to mutation greatly increases risk of ...
Cancer
Jan 16, 2013 |
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Tiny tools help advance medical discoveries: Researchers are designing tools to analyze cells at the microscale
To understand the progression of complex diseases such as cancer, scientists have had to tease out the interactions between cells at progressively finer scales—from the behavior of a single tumor cell in ...
Medical research
Jan 08, 2013 |
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Inherited retinal disease research may lead to treatment
Inherited retinal disease is a major cause of vision impairment in early life - and a researcher at The University of Western Australia hopes a study in which he was involved will contribute towards the development ...
Medical research
Jan 08, 2013 |
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Why good resolutions about taking up a physical activity can be hard to keep
Physical inactivity is a major public health problem that has both social and neurobiological causes. According to the results of an Ipsos survey published on Monday 31 Dec., the French have put "taking up ...
Psychology & Psychiatry
Jan 04, 2013 |
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New study finds key mechanism in calcium regulation
All living cells keep their cellular calcium concentration at a very low level. Since a small increase in calcium can affect many critical cellular functions (an elevated calcium concentration over an extended period can ...
Neuroscience
Jan 03, 2013 |
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Researchers uncover novel role of BRCA1 in regulating the survival of skin stem cells
Our DNA, which stores our genetic information, is constantly exposed to damage. If not properly repaired, DNA damage can lead to cell death. This, in turn, can lead to tissue exhaustion and ageing, or induce mutations resulting ...
Cancer
Jan 03, 2013 |
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The factor that could influence future breast cancer treatment
Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...
Cancer
Dec 27, 2012 |
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FDA: Pradaxa not for patients with mechanical heart valves
(HealthDay)—The blood thinner Pradaxa should not be used to prevent stroke or blood clots in patients with mechanical heart valves, the U.S. Food and Drug Administration said in a warning issued Wednesday.
Cardiology
Dec 21, 2012 |
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Toasting your health: Take care with alcohol consumption
(Medical Xpress)—The holidays are a time to consume—food, gifts, and spirits. Here are a few alcohol-related story ideas from The Methodist Hospital. Because alcohol's effects on human physiology are complex, advice about ...
Health
Dec 20, 2012 |
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Worries about dementia: How hospitalization affects the elderly
Older people often worry about dementia and while some risks are known, for example alcoholism or stroke, the effects of illness are less clear. New research published in BioMed Central's open access journal Critical Care looks ...
Alzheimer's disease & dementia
Dec 16, 2012 |
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The brain recruits its own decision-making circuits to simulate how other people make decisions
A team of researchers led by Hiroyuki Nakahara and Shinsuke Suzuki of the RIKEN Brain Science Institute has identified a set of brain structures that are critical for predicting how other people make decisions.
Neuroscience
Dec 14, 2012 |
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