With advances in medical science driving progress against childhood brain tumors, today three out of four young patients survive at least five years beyond diagnosis. However, the outcomes look grim when malignant cells spread, ...
Jun 29, 2021
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Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer.
May 20, 2021
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Scientists from Queen Mary University of London, funded by the charity Brain Tumor Research, have found a new way to starve cancerous brain tumor cells of energy in order to prevent further growth.
Apr 12, 2021
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Scientists at St. Jude Children's Research Hospital and their colleagues have published a detailed account of SJMB03, a clinical trial for pediatric patients with medulloblastoma. Additionally, they report results of the ...
Jan 27, 2021
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Johns Hopkins researchers have discovered a new diagnostic marker that distinguishes a fast-growing type of the pediatric brain cancer medulloblastoma from a less aggressive type. The researchers hope that this biomarker ...
Dec 10, 2020
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Scientists at Sanford Burnham Prebys Medical Discovery Institute, University of California San Diego School of Medicine and Hopp Children's Cancer Center Heidelberg (KiTZ) have demonstrated that personalized drug screens ...
Nov 12, 2020
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Investigators at St. Jude Children's Research Hospital, the European Molecular Biology Laboratory, and the German Cancer Research Center have identified ELP1 as a novel predisposition gene in the SHH subgroup of pediatric ...
Apr 1, 2020
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Investigators at St. Jude Children's Research Hospital have found that the ABCC4 transporter is critical to the SHH signaling pathway in the brain tumor medulloblastoma. This work provides a rationale for development of small ...
Mar 31, 2020
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A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer—and potentially many others.
Feb 13, 2020
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Medication prescribed for a certain type of epilepsy may offer a new method for treating malignant infantile brain tumors. A specific mTOR inhibitor has the ability to cross the blood-brain barrier to both reach and attack ...
Nov 29, 2019
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