Long-term cognitive problems are a frequent side effect in children undergoing life-saving radiation therapy for medulloblastoma—the most common malignant pediatric brain tumor. Medulloblastoma affects between 250 and 500 ...
Jul 10, 2019
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Scientists at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have identified a protein critical to both the normal development of the brain and, in many cases, the development of medulloblastoma, a fast-growing ...
Mar 26, 2015
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St. Jude Children's Research Hospital scientists have gained ground toward developing more targeted therapies for the most common childhood brain tumor. The findings appear today in the Journal of Molecular Biology.
May 8, 2015
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The most comprehensive analysis yet of medulloblastoma has identified genomic changes responsible for more than 75 percent of the brain tumors, including two new suspected cancer genes that were found exclusively in the least ...
Jul 19, 2017
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Copper has been clinically improving the lives of people since about 1500 BCE, when an Egyptian physician first recorded its use as a treatment for inflammation. Some 35 centuries later, researchers at Johns Hopkins Medicine ...
Nov 3, 2021
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Investigators at St. Jude Children's Research Hospital have found that the ABCC4 transporter is critical to the SHH signaling pathway in the brain tumor medulloblastoma. This work provides a rationale for development of small ...
Mar 31, 2020
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Effective and safe treatments are needed for medulloblastoma—the most common type of cancerous brain tumor in children—especially for patients whose cancer has spread to the spinal cord. A recent phase I clinical trial ...
Jul 14, 2022
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Children diagnosed with the most common paediatric malignant brain cancer, medulloblastoma, will benefit from more targeted treatment following the identification of genetic mutations in the cancer.
Jun 26, 2012
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University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.
Oct 24, 2019
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New research published in Nature Communications from scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U), in collaboration with the Stanford University School of Medicine, shows a specific protein ...
Oct 11, 2018
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