Oncology & Cancer

How immune cells in the tumor microenvironment make things worse

Cells from the immune system called CD4+ regulatory T cells, or simply Treg, are linked to tumor prognosis: the more Treg cells present in a tumor, the worst the prognosis. We know from previous research studies that Treg ...

Oncology & Cancer

CAR-T immunotherapy could be improved to kill solid tumors

Immunotherapy, which harnesses the power of the body's immune system to fight disease, is gaining huge traction in treating cancer. Chief among cancer immunotherapies is a treatment known as CAR-T, or chimeric antigen receptor ...

Medical research

Protein linked to aggressive skin cancer

Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common ...

Genetics

Eye color may indicate risk for serious skin conditions

Eye color may be an indicator of whether a person is high-risk for certain serious skin conditions. A study, led by the University of Colorado School of Medicine, shows people with blue eyes are less likely to have vitiligo. ...

Immunology

Mechanism for resistance to immunotherapy treatment discovered

An urgent question for cancer scientists is why immunotherapy achieves dramatic results in some cases but doesn't help most patients. Now, two research groups from Dana-Farber Cancer Institute have independently discovered ...

Oncology & Cancer

Shedding light on 100-year-old cancer mystery

For almost a century, scientists have observed a strange behavior in cancer cells: They prefer a less-efficient pathway to produce energy. While normal cells utilize aerobic glycolysis to use glucose to produce 36 energy-storing ...

Medical research

Some skin cancers may start in hair follicles

Some of the most deadly skin cancers may start in stem cells that lend color to hair, and originate in hair follicles rather than in skin layers, a new study finds.

Oncology & Cancer

Fighting cancer with the help of someone else's immune cells

A new step in cancer immunotherapy: researchers from the Netherlands Cancer Institute and University of Oslo/Oslo University Hospital show that even if one's own immune cells cannot recognize and fight their tumors, someone ...

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