Study reveals how melanoma evades chemotherapy
Nitric oxide (NO), a gas with many biological functions in healthy cells, can also help some cancer cells survive chemotherapy. A new study from MIT reveals one way in which this resistance may arise, and ...
Cancer
Apr 08, 2013 |
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Immortality gene mutation identifies brain tumors, other cancers
Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...
Cancer
Mar 18, 2013 |
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Tumors deliberately create conditions that inhibit body's best immune response
New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune respon ...
Cancer
Mar 01, 2013 |
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New mutations driving malignant melanoma discovered
Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't ...
Cancer
Jan 24, 2013 |
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Drug-resistant melanoma tumors shrink when therapy is interrupted
Researchers in California and Switzerland have discovered that melanomas that develop resistance to the anti-cancer drug vemurafenib (marketed as Zelboraf), also develop addiction to the drug, an observation ...
Cancer
Jan 09, 2013 |
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Eye color may indicate risk for serious skin conditions
Eye color may be an indicator of whether a person is high-risk for certain serious skin conditions. A study, led by the University of Colorado School of Medicine, shows people with blue eyes are less likely to have vitiligo. ...
Genetics
May 06, 2012 |
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Using patients' own tumor-fighting cells to knock back advanced melanoma
A small, early-phase clinical trial to test the effectiveness of treating patients with advanced melanoma using billions of clones of their own tumor-fighting cells combined with a specific type of chemotherapy has shown ...
Cancer
Mar 05, 2012 |
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Researchers engineer blood stem cells to fight melanoma
Researchers from UCLA's cancer and stem cell centers have demonstrated for the first time that blood stem cells can be engineered to create cancer-killing T-cells that seek out and attack a human melanoma. The researchers ...
Cancer
Nov 28, 2011 |
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Red hair pigment might raise melanoma risk, study says
(HealthDay)—The red in redheads' hair is thought to put them at increased risk of the dangerous skin cancer melanoma, even if they don't spend a lot of time in the sun, according to a new study.
Cancer
May 09, 2013 |
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New study reveals how tumor suppressor p53 shut down in metastatic melanoma
Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way ...
Cancer
Apr 25, 2013 |
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Shutting down DNA construction: How senescence halts growth of potential cancers
Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks ...
Cancer
Apr 04, 2013 |
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Research on immune-cell therapy could strengthen promising melanoma treatment
A new study of genetically modified immune cells by scientists from UCLA and the California Institute of Technology could help improve a promising treatment for melanoma, an often fatal form of skin cancer.
Cancer
Mar 22, 2013 |
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BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
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Hope in stopping melanoma from spreading: Study shows that inhibiting key protein prevents metastasis to lungs in mice
(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation ...
Cancer
Mar 05, 2013 |
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Gene identified in some melanoma linked to increased resistance to treatment
(Medical Xpress)—Scientists at Queen Mary, University of London have identified a gene present in some melanoma which appears to make the tumour cells more resistant to treatment, according to research ...
Cancer
Feb 19, 2013 |
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