News tagged with membrane proteins
Study of the machinery of cells reveals clues to neurological disorder
(Medical Xpress)—Investigation by researchers from the University of Exeter and ETH Zurich has shed new light on a protein which is linked to a common neurological disorder called Charcot-Marie-Tooth disease.
Neuroscience
May 16, 2013 |
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Research to end asbestos-related cancer
Scientists from Flinders University are trying to develop a new treatment for a highly aggressive, asbestos-related lung cancer that is set to become more prevalent in the future.
Cancer
May 16, 2013 |
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Study uses Botox to find new wrinkle in brain communication
National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel ...
Medical research
May 02, 2013 |
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Making a window for drug delivery in the blood-brain barrier
(Medical Xpress)—The blood-brain barrier (BBB) prevents most large or hydrophilic (polar) molecules from getting into the brain. For many neurological diseases, like Parkinson's, the presence of the BBB ...
Medical research
Apr 30, 2013 |
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Food dye could provide 'blueprint' for treatment of Panx1-related diseases
The food dye Brilliant Blue FCF (BB FCF) could be a useful tool in the development of treatments for a variety of conditions involving the membrane channel protein Pannexin 1(Panx1), according to a study in The Journal of General Physi ...
Medical research
Apr 29, 2013 |
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Fusion and cell death in the development of skeletal muscle
(Medical Xpress)—Membrane fusion is a highly regulated event, both inside cells, and between them. From the moment a sperm first fuses with an egg, subsequent developmental events depend upon its proper ...
Medical research
Apr 26, 2013 |
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Study reveals natural process that blocks viruses
The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable ...
Medical research
Apr 17, 2013 |
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Recipe for large numbers of stem cells requires only one ingredient
Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...
Medical research
Apr 17, 2013 |
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Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer
Platinum compounds, such as cisplatin and carboplatin, induce DNA cross-linking, prohibiting DNA synthesis and repair in rapidly dividing cells. They are first line therapeutics in the treatment of many solid tumors, but ...
Cancer
Apr 15, 2013 |
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Cholesterol rafts deliver drugs inside cancer cells
DNA, siRNA and miRNA can reprogram cancer cells – that is, if these nucleic acids could cross through the cell membrane. A University of Colorado Cancer Center study published today in the journal Therapeutic Delivery shows ...
Cancer
Apr 02, 2013 |
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Certain breast cancers have a trait that could be attacked by new therapies
More than 100 women per day die from breast cancer in the United States. The odds of developing breast cancer increase for women taking hormone replacement therapy to avoid the effects of menopause. New research by University ...
Cancer
Mar 27, 2013 |
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New research looks at novel ways to combat drug resistance
University of Southampton biological scientists are leading a major research project aimed at making drugs more effective.
Medical research
Mar 27, 2013 |
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Protein in fat cells that stimulates inflammatory signaling helps put gears in motion for onset of diet-induced obesity
Poor diet and lifestyle choices set the stage for obesity and diabetes, but the immune system plays a relatively underappreciated role in accelerating this process. Metabolic changes in fat cells stimulate ...
Medical research
Mar 15, 2013 |
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From shape-shifting to therapy
(Medical Xpress)—The latest research into the intricate processes that let substances into and out of cells will help to lay the foundations for the next generation of therapies for major diseases.
Medical research
Mar 12, 2013 |
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Why a hereditary anemia is caused by genetic mutation in mechanically sensitive ion channel
A genetic mutation that alters the kinetics of an ion channel in red blood cells has been identified as the cause behind a hereditary anemia, according to a paper published this month in the Proceedings of the National Ac ...
Medical research
Mar 08, 2013 |
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Membrane protein
A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. More than half of all proteins interact with membranes.
Biological membranes consist of a phospholipid bilayer and a variety of proteins that accomplish vital biological functions. Structural proteins are attached to microfilaments in the cytoskeleton which ensures stability of the cell. Cell recognition proteins allow cells to identify each other and interact. Such proteins are involved in immune response, for example. Membrane enzymes produce a variety of substances essential for cell function. Membrane receptor proteins serve as connection between the cell's internal and external environments. Finally, transport proteins play an important role in the maintenance of concentrations of ions. These transport proteins come in two forms: carrier proteins and channel proteins. Carrier proteins are involved in using the energy released from ATP being broken down to facilitate active transport and ion exchange. These processes ensure that useful substances are able to enter the cell and that toxic substances are pumped out of the cell.
For more information about Membrane protein, read the full article at
Wikipedia.
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