Alzheimer's disease & dementia

New information on the pathological mechanisms of Alzheimer's disease

Researchers at the University of Helsinki have discovered a mechanism by which harmful tau protein aggregates are transmitted between neurons. Alongside amyloid plaques, tau aggregates in the brain are a significant factor ...

Medical research

Reproducing pediatric kidney disease from human iPS cells

Scientists in Japan have found a "skeleton key" for congenital kidney disease research. Using iPS cells generated from the skin cells of a patient with a nephrin mutation, Kumamoto University scientists have successfully ...

Diseases, Conditions, Syndromes

Scientists sweep cellular neighborhoods where Zika hides out

Most people infected with Zika never show symptoms. But the virus sometimes causes severe disability—from microcephaly in babies to weakness or partial paralysis in adults—and there is no treatment. In a recent study ...

Parkinson's & Movement disorders

Function of gene mutations linked to neurological diseases identified

Several gene mutations have been linked to Parkinson's disease, but exactly how and where some of them cause their damage has been unclear. A new Yale study, published in the Journal of Cell Biology, shows that one of the ...

Oncology & Cancer

Researchers uncover new target to stop cancer growth

Researchers at the University of Wisconsin-Madison have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes—tiny, membrane-bound packages containing proteins and RNAs that stimulate ...

Diseases, Conditions, Syndromes

Finally, hope for a syphilis vaccine

Despite efforts to eradicate it, syphilis is on the rise. Until now, most health agencies focused on treating infected people and their sex partners but new discoveries may make a vaccine possible, UConn Health researchers ...

Diseases, Conditions, Syndromes

Hitting virus infections where it hurts

Virus infection starts at the cell surface with interactions between viral and host proteins that bind together. Researchers are working on ways to lock out the virus or prevent it from reproducing in the cell by targeting ...

Immunology

Toxin floats on lipid rafts

Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...

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