News tagged with messenger rna
Related topics: protein , gene expression , rna molecules , cells , genes
New compound holds promise for treating Duchenne MD, other inherited diseases
Scientists at UCLA have identified a new compound that could treat certain types of genetic disorders in muscles. It is a big first step in what they hope will lead to human clinical trials for Duchenne muscular dystrophy.
Genetics
Jun 27, 2012 |
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MicroRNAs link the pathways that control growth during animal development and in disease
Cellular mechanisms that enable healthy growth can spiral out of control and give rise to cancer. For this reason, signal transduction pathways that underlie cell growth are tightly regulated, with multiple ...
Medical research
Jun 20, 2012 |
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RNA regulator of melanoma could be a new target for cancer therapy
Melanoma is the most deadly form of skin cancer, estimated by the National Cancer Institute to afflict more than 70,000 people in the United States annually and the incidence rate continues to rise. In a study published online ...
Cancer
May 10, 2012 |
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Think global, act local: New roles for protein synthesis at synapses
(Medical Xpress) -- How do we build a memory in the brain? It is well known that for animals (and humans) new proteins are needed to establish long-term memories. During learning information is stored at the synapses, the ...
Neuroscience
May 10, 2012 |
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Low oxygen levels could drive cancer growth
Low oxygen levels in cells may be a primary cause of uncontrollable tumor growth in some cancers, according to a new University of Georgia study. The authors' findings run counter to widely accepted beliefs that genetic mutations ...
Cancer
May 03, 2012 |
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Coordinating the circadian clock: Researchers find that molecular pair controls time-keeping and fat metabolism
(PhysOrg.com) -- The 24-hour internal clock controls many aspects of human behavior and physiology, including sleep, blood pressure, and metabolism. Disruption in circadian rhythms leads to increased incidence of many diseases, ...
Genetics
Apr 04, 2012 |
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Compound that halts growth of malaria parasite created
A drug candidate that has shown promise for neutralizing dangerous bacteria also prevents the parasite that causes malaria from growing, new research by a Yale University team headed by Nobel laureate Sidney Altman shows.
Medical research
Apr 02, 2012 |
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PI3K/mTOR pathway proteins tied to poor prognosis in breast cancer
Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...
Cancer
Apr 01, 2012 |
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Fewer mitochondria in offspring of parents with diabetes
(HealthDay) -- Normal-weight, insulin-resistant individuals whose parents have type 2 diabetes have fewer mitochondria in their muscles due to lower expression of lipoprotein lipase (LPL), according to a study ...
Diabetes
Mar 26, 2012 |
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Intratumor heterogeneity seen in renal carcinomas
(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study ...
Cancer
Mar 08, 2012 |
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Will a genetic mutation cause trouble? Ask Spliceman
In a brief paper in the journal Bioinformatics, Brown University researchers describe a new, freely available Web-based program called Spliceman for predicting whether genetic mutations are likely to disrupt the splicing of mes ...
Genetics
Mar 05, 2012 |
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Link found between MicroRNA and neurological aging in fruit flies
(Medical Xpress) -- Researchers from several institutions in the Philadelphia area have banded together to form a team to look into the possible impact a certain type of MicroRNA (miRNA) may have on the neurological ...
Medical research
Feb 16, 2012 |
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New HIV-vaccine tested on people
Scientists from the Antwerp Institute of Tropical Medicine, Antwerp University Hospital and Antwerp University have tested a new 'therapeutic vaccine' against HIV on volunteers. The participants were so to say vaccinated ...
HIV & AIDS
Feb 13, 2012 |
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No brakes on breast cancer cells
Scientists of the German Cancer Research Center have discovered a tiny RNA molecule, called miR-520, which at once blocks two important pathways in the development of cancer in cells. In estrogen receptor-negative ...
Cancer
Dec 16, 2011 |
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Long non-coding RNA prevents the death of maturing red blood cells
A long non-coding RNA (lncRNA) regulates programmed cell death during one of the final stages of red blood cell differentiation, according to Whitehead Institute researchers. This is the first time a lncRNA has been found ...
Genetics
Dec 07, 2011 |
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