News tagged with metabolic diseases
Brain region may hold key to aging
While the search continues for the Fountain of Youth, researchers may have found the body's "fountain of aging": the brain region known as the hypothalamus. For the first time, scientists at Albert Einstein ...
Neuroscience
May 01, 2013 |
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When you eat matters: Study offers drug-free intervention to prevent obesity, diabetes
It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override ...
Medical research
May 17, 2012 |
4.8 / 5 (17) |
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How belly fat differs from thigh fat—and why it matters
Men tend to store fat in the abdominal area, but don't usually have much in the way of hips or thighs. Women, on the other hand, are more often pear-shaped—storing more fat on their hips and thighs than in the belly. Why ...
Medical research
Jan 11, 2013 |
4.8 / 5 (14) |
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Study offers insight to how fructose causes obesity, metabolic syndrome
A group of scientists from across the world have come together in a just-published study that provides new insights into how fructose causes obesity and metabolic syndrome, more commonly known as diabetes.
Medical research
Feb 27, 2012 |
4.9 / 5 (11) |
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Whole exome sequencing identifies cause of metabolic disease
Sequencing a patient's entire genome to discover the source of his or her disease is not routine – yet. But geneticists are getting close.
Genetics
Feb 03, 2012 |
5 / 5 (9) |
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Biologists find potential drug that speeds cellular recycling
A University of Michigan cell biologist and his colleagues have identified a potential drug that speeds up trash removal from the cell's recycling center, the lysosome.
Medical research
Mar 13, 2012 |
5 / 5 (9) |
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A new candidate pathway for treating visceral obesity
Brown seems to be the color of choice when it comes to the types of fat cells in our bodies. Brown fat expends energy, while its counterpart, white fat stores it. The danger in white fat cells, along with the increased risk ...
Medical research
May 06, 2012 |
5 / 5 (8) |
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Lipid researcher, 98, reports on the dietary causes of heart disease
A 98-year-old researcher argues that, contrary to decades of clinical assumptions and advice to patients, dietary cholesterol is good for your heart – unless that cholesterol is unnaturally oxidized (by ...
Cardiology
Feb 27, 2013 |
5 / 5 (8) |
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New study reveals that every single junk food meal damages your arteries
A single junk food meal – composed mainly of saturated fat – is detrimental to the health of the arteries, while no damage occurs after consuming a Mediterranean meal rich in good fats such as mono-and polyunsaturated ...
Health
Oct 30, 2012 |
3.9 / 5 (10) |
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Discovery of new hormone opens doors to new type 2 diabetes treatments
Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in ...
Diabetes
May 07, 2013 |
4.6 / 5 (8) |
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Researcher contends multiple sclerosis is not a disease of the immune system
An article to be published Friday (Dec. 23) in the December 2011 issue of The Quarterly Review of Biology argues that multiple sclerosis, long viewed as primarily an autoimmune disease, is not actually a disease of the im ...
Immunology
Dec 22, 2011 |
4.5 / 5 (8) |
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Lift weights to lower blood sugar? White muscle helps keep blood glucose levels under control
Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.
Medical research
Apr 07, 2013 |
4.9 / 5 (7) |
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Blocking natural, marijuana-like chemical in the brain boosts fat burning
Stop exercising, eat as much as you want ... and still lose weight? It sounds impossible, but UC Irvine and Italian researchers have found that by blocking a natural, marijuana-like chemical regulating energy metabolism, ...
Medical research
Mar 06, 2012 |
4.8 / 5 (6) |
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Protective gene in fat cells may lead to therapeutic for Type 2 diabetes
In a finding that may challenge popular notions of body fat and health, researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown how fat cells can protect the body against diabetes. The results may lead to a ...
Medical research
Apr 01, 2012 |
4.8 / 5 (6) |
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New study uncovers probable mechanism underlying resveratrol activity
National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits. The authors present ...
Medical research
Feb 02, 2012 |
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Inborn error of metabolism
Inborn errors of metabolism comprise a large class of genetic diseases involving disorders of metabolism. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substances (substrates) into others (products). In most of the disorders, problems arise due to accumulation of substances which are toxic or interfere with normal function, or to the effects of reduced ability to synthesize essential compounds. Inborn errors of metabolism are now often referred to as congenital metabolic diseases or inherited metabolic diseases, and these terms are considered synonymous.
The term inborn error of metabolism was coined by a British physician, Archibald Garrod (1857-1936), in the early 20th century (1908). He is known for work that prefigured the "one gene, one enzyme" hypothesis, based on his studies on the nature and inheritance of alkaptonuria. His seminal text, Inborn Errors of Metabolism was published in 1923.
For more information about Inborn error of metabolism, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
