Medical research

SIRT5 regulation of proteins involved in metabolism

The Sirtuin family of protein deacylases has received considerable attention in recent years due to its links to longevity, diabetes, cancer, and metabolic regulation. In a new study published in the Dec. 3rd 2013 issue of ...

Oncology & Cancer

Blocking key enzyme in cancer cells could lead to new therapy

Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer—and they believe it could be exploited as a target to develop ...

Overweight & Obesity

Simvastatin blunts benefits of exercise in overweight, obese

(HealthDay)—Cholesterol-lowering therapy with simvastatin reduces the physiological responses to aerobic exercise training in overweight or obese adults who are at increased risk for metabolic syndrome, according to research ...

Oncology & Cancer

Kidney cancer progression linked to shifts in tumor metabolism

Investigators in The Cancer Genome Atlas (TCGA) Research Network have uncovered a connection between how tumor cells use energy from metabolic processes and the aggressiveness of the most common form of kidney cancer, clear ...

Diseases, Conditions, Syndromes

Therapy helps regenerate child's undeveloped bones

Four years ago, Janelly Martinez-Amador was confined to a bed, unable to move even an arm or lift her head. At age 3, the fragile toddler had the gross motor skills of a newborn and a ventilator kept her alive.

Oncology & Cancer

Diabetes drug could hold promise for lung cancer patients

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work ...

Diseases, Conditions, Syndromes

Canada launches first gene therapy trial for Fabry disease

Researchers in Calgary have launched the first gene therapy clinical trial in the world for Fabry disease, a rare inherited enzyme deficiency that can shorten the lifespan of people who have it by as much as 40 years.

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