News tagged with metabolic enzyme
Cancer suppressor gene links metabolism with cellular aging
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Cancer
Jan 13, 2013 |
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Scientists identify molecular process in fat cells that influences stress and longevity
As part of their ongoing research investigating the biology of aging, the greatest risk factor for type 2 diabetes and other serious diseases, scientists at Joslin Diabetes Center have identified a new factor—microRNA ...
Medical research
Sep 26, 2012 |
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Circadian rhythms can be modified for potential treatment of disorders
(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Cardiology
Jan 22, 2013 |
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Mystery gene reveals new mechanism for anxiety disorders
A novel mechanism for anxiety behaviors, including a previously unrecognized inhibitory brain signal, may inspire new strategies for treating psychiatric disorders, University of Chicago researchers report.
Genetics
May 15, 2012 |
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Scientists link 'oncometabolite' to onset of acute myeloid leukemia
A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme ...
Cancer
Jul 04, 2012 |
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Inflammation controlled differently in brain and other tissues, study finds
A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it.
Medical research
Oct 20, 2011 |
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Discovery represents 'new paradigm' in the way drugs can be manufactured
Robert Linhardt is working to forever change the way some of the most widely used drugs in the world are manufactured. Today, in the journal Science, he and his partner in the research, Jian Liu, have announ ...
Medications
Oct 27, 2011 |
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Therapy helps regenerate child's undeveloped bones
Four years ago, Janelly Martinez-Amador was confined to a bed, unable to move even an arm or lift her head. At age 3, the fragile toddler had the gross motor skills of a newborn and a ventilator kept her ...
Diseases, Conditions, Syndromes
Apr 24, 2013 |
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Diabetes drug could hold promise for lung cancer patients
Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases ...
Cancer
Jan 29, 2013 |
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How genetics shape our addictions: Genes predict the brain's reaction to smoking
Have you ever wondered why some people find it so much easier to stop smoking than others? New research shows that vulnerability to smoking addiction is shaped by our genes.
Genetics
Sep 11, 2012 |
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Multi-functional anti-inflammatory/anti-allergic developed
A synthetic, anti-inflammatory and anti-allergic family of drugs to combat a variety of illnesses while avoiding detrimental side effects has been developed by a Hebrew University of Jerusalem researcher.
Inflammatory disorders
Sep 06, 2012 |
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Calcium, vitamin D modulate human energy metabolism
(HealthDay) -- There is considerable evidence that calcium and vitamin D intake are influential in modulating energy metabolism in humans, according to a study published online March 2 in Obesity Reviews.
Health
Mar 12, 2012 |
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Cord blood effective alternative to matched donor stem cells for kids with rare disorder
Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating disease known as Hurler's ...
Medical research
Mar 14, 2013 |
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Lack of key enzyme in the metabolism of folic acid leads to birth defects
Researchers at The University of Texas at Austin have discovered that the lack of a critical enzyme in the folic acid metabolic pathway leads to neural tube birth defects in developing embryos.
Medical research
Jan 17, 2013 |
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Plants may be key to diabetes treatment
(Medical Xpress) -- With the growing worldwide incidence of diabetes, a new study reveals that traditional Aboriginal and Indian plant extracts show potential for managing the disease.
Diabetes
Jun 29, 2012 |
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