News tagged with metabolic enzymes
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Cancer Jan 13, 2013 | 3.7 / 5 (3) | 0 |
As part of their ongoing research investigating the biology of aging, the greatest risk factor for type 2 diabetes and other serious diseases, scientists at Joslin Diabetes Center have identified a new factor—microRNA ...
Medical research Sep 26, 2012 | 5 / 5 (5) | 1 |
(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Cardiology Jan 22, 2013 | 2 / 5 (2) | 0 |
A novel mechanism for anxiety behaviors, including a previously unrecognized inhibitory brain signal, may inspire new strategies for treating psychiatric disorders, University of Chicago researchers report.
Genetics May 15, 2012 | 4.5 / 5 (4) | 0 |
A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme ...
Cancer Jul 04, 2012 | 5 / 5 (3) | 0 |
A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it.
Medical research Oct 20, 2011 | 4.9 / 5 (7) | 1 |
Robert Linhardt is working to forever change the way some of the most widely used drugs in the world are manufactured. Today, in the journal Science, he and his partner in the research, Jian Liu, have announ ...
Medications Oct 27, 2011 | 5 / 5 (3) | 0 |
Four years ago, Janelly Martinez-Amador was confined to a bed, unable to move even an arm or lift her head. At age 3, the fragile toddler had the gross motor skills of a newborn and a ventilator kept her ...
Diseases, Conditions, Syndromes Apr 24, 2013 | not rated yet | 0
Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases ...
Cancer Jan 29, 2013 | not rated yet | 0 |
Have you ever wondered why some people find it so much easier to stop smoking than others? New research shows that vulnerability to smoking addiction is shaped by our genes.
Genetics Sep 11, 2012 | 5 / 5 (1) | 0 |
A synthetic, anti-inflammatory and anti-allergic family of drugs to combat a variety of illnesses while avoiding detrimental side effects has been developed by a Hebrew University of Jerusalem researcher.
Inflammatory disorders Sep 06, 2012 | 5 / 5 (3) | 0
(HealthDay) -- There is considerable evidence that calcium and vitamin D intake are influential in modulating energy metabolism in humans, according to a study published online March 2 in Obesity Reviews.
Health Mar 12, 2012 | not rated yet | 0
Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating disease known as Hurler's ...
Medical research Mar 14, 2013 | 5 / 5 (1) | 0
Researchers at The University of Texas at Austin have discovered that the lack of a critical enzyme in the folic acid metabolic pathway leads to neural tube birth defects in developing embryos.
Medical research Jan 17, 2013 | not rated yet | 0 |
(Medical Xpress) -- With the growing worldwide incidence of diabetes, a new study reveals that traditional Aboriginal and Indian plant extracts show potential for managing the disease.
Diabetes Jun 29, 2012 | 5 / 5 (2) | 0