International consortium builds 'Google Map' of human metabolism
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction ...
Medical research
Mar 03, 2013 |
3.8 / 5 (5) |
4
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Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
5 / 5 (4) |
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Cancer suppressor gene links metabolism with cellular aging
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Cancer
Jan 13, 2013 |
3.7 / 5 (3) |
0
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Lift weights to lower blood sugar? White muscle helps keep blood glucose levels under control
Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.
Medical research
Apr 07, 2013 |
4.9 / 5 (7) |
0
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Study uncovers mechanism for how grapes reduce heart failure associated with hypertension
A study appearing in the Journal of Nutritional Biochemistry demonstrates that grapes are able to reduce heart failure associated with chronic high blood pressure (hypertension) by increasing the activity of several genes ...
Cardiology
May 02, 2013 |
4.8 / 5 (4) |
0
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Single gene cause of insulin sensitivity may offer insight for treating diabetes
(Medical Xpress)—The first single gene cause of increased sensitivity to the hormone insulin has been discovered by a team of Oxford University researchers.
Diabetes
Sep 12, 2012 |
5 / 5 (3) |
0
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Common nutritional supplement offers promise in treatment of unique form of autism with epilepsy
An international team of researchers, led by scientists at the University of California, San Diego and Yale University schools of medicine, have identified a form of autism with epilepsy that may potentially be treatable ...
Autism spectrum disorders
Sep 06, 2012 |
3 / 5 (3) |
0
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Study identifies genes, pathways altered during relaxation response practice
A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) finds that elicitation of the relaxation response ...
Psychology & Psychiatry
May 01, 2013 |
5 / 5 (1) |
0
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Cancer cell metabolism kills
Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...
Cancer
Apr 15, 2013 |
5 / 5 (7) |
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Blocking telomerase kills cancer cells but provokes resistance, progression
Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Cancer
Feb 21, 2012 |
5 / 5 (2) |
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Metabolic MAGIC: Meta-analyses reveal new genetic regions influencing blood glucose traits
Researchers have identified 38 new genetic regions that are associated with glucose and insulin levels in the blood. This brings the total number of genetic regions associated with glucose and insulin levels to 53, over half ...
Genetics
Aug 12, 2012 |
5 / 5 (1) |
0
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When timing is everything: Research says beneficial mutations need specific circumstances to win out
When it comes to the sort of beneficial mutations that drive natural selection, there's new evidence that, evolutionarily speaking, timing is everything.
Genetics
Mar 20, 2013 |
5 / 5 (1) |
4
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Chemists determine one way tumors meet their growing need
Behaving something like ravenous monsters, tumors need plentiful supplies of cellular building blocks such as amino acids and nucleotides in order to keep growing at a rapid pace and survive under harsh conditions. ...
Cancer
Aug 23, 2012 |
5 / 5 (1) |
0
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Study reveals how diabetes drug delays ageing in worms
A widely prescribed type 2 diabetes drug slows down the ageing process by mimicking the effects of dieting, according to a study published today using worms to investigate how the drug works.
Medical research
Mar 28, 2013 |
4.5 / 5 (2) |
0
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Scientists find potential loophole in pancreatic cancer defenses
Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control ...
Cancer
Mar 27, 2013 |
5 / 5 (4) |
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