Team finds mechanism that regulates production of energy-burning brown fat
Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue ...
Medical research
Mar 13, 2013 |
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Normal prion protein regulates iron metabolism
An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.
Alzheimer's disease & dementia
Mar 13, 2013 |
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Bitter melon juice prevents pancreatic cancer in mouse models
A University of Colorado Cancer study published this week in the journal Carcinogenesis shows that bitter melon juice restricts the ability of pancreatic cancer cells to metabolize glucose, thus cutting the cells' energy ...
Cancer
Mar 12, 2013 |
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Study finds fat and bone mass are genetically linked
When it comes to body shape, diet and exercise can only take us so far. Our body shape and geometry are largely determined by genetic factors. Genetics also have an impact on our body composition – including soft fat tissue ...
Medical research
Mar 11, 2013 |
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Neonatal size unaffected by gestational diabetes drugs
(HealthDay)—Women with gestational diabetes mellitus treated with metformin or insulin have similar changes in markers of metabolic status and no differences in offspring birth weight, according to a study ...
Diabetes
Mar 08, 2013 |
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Weight loss may prevent, treat osteoarthritis in obese patients
Weight loss may prevent and significantly alleviate the symptoms of osteoarthritis, a progressive disease of the joints known as "wear and tear" arthritis, according to a literature review appearing in the March 2013 issue ...
Surgery
Mar 08, 2013 |
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Enhanced brain acetate metabolism may reward heavy drinkers
In addition to its well-known effects on the CNS, alcohol consumption has a significant impact on metabolism. After consumption, the body rapidly begins converting ethanol to acetate, which can serve as an energy source for ...
Addiction
Mar 08, 2013 |
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BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
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Cancer-promoting protein found to also suppress cell growth
Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...
Medical research
Mar 07, 2013 |
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Researchers find molecular switch turning on self-renewal of liver damage
The liver is one of the few organs in our body that can regenerate itself, but how it occurs is a biological mystery. New research from BRIC, University of Copenhagen and the Finsen Laboratory, Rigshospitalet, ...
Medical research
Mar 07, 2013 |
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PTSD linked to insulin resistance and metabolic syndrome, early markers of heart disease
Patients diagnosed with post-traumatic stress disorder (PTSD) have a significantly higher risk of developing insulin resistance and metabolic syndrome, placing them at greater risk for heart disease and diabetes, according ...
Cardiology
Mar 07, 2013 |
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Obesity makes fat cells act like they're infected
(Medical Xpress)—The inflammation of fat tissue is part of a spiraling series of events that leads to the development of type 2 diabetes in some obese people. But researchers have not understood what triggers ...
Medical research
Mar 05, 2013 |
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Discovery of human genetic mutation could lead to new treatments for type 1 diabetes
In type 1 diabetes, the immune system destroys insulin-producing cells in the pancreas, but the precise cause has not been clear. A study published by Cell Press on March 5th in Cell Metabolism reveals that a ...
Genetics
Mar 05, 2013 |
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Recon 2 modeling may help tailor treatments for patients with metabolic diseases, cancer
An international team of researchers, including an investigator with the Virginia Bioinformatics Institute at Virginia Tech, has produced what may be the most comprehensive computer model of human metabolism yet developed.
Medical research
Mar 04, 2013 |
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International consortium builds 'Google Map' of human metabolism
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction ...
Medical research
Mar 03, 2013 |
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