BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
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Cancer-promoting protein found to also suppress cell growth
Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...
Medical research
Mar 07, 2013 |
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Researchers find molecular switch turning on self-renewal of liver damage
The liver is one of the few organs in our body that can regenerate itself, but how it occurs is a biological mystery. New research from BRIC, University of Copenhagen and the Finsen Laboratory, Rigshospitalet, ...
Medical research
Mar 07, 2013 |
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PTSD linked to insulin resistance and metabolic syndrome, early markers of heart disease
Patients diagnosed with post-traumatic stress disorder (PTSD) have a significantly higher risk of developing insulin resistance and metabolic syndrome, placing them at greater risk for heart disease and diabetes, according ...
Cardiology
Mar 07, 2013 |
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Obesity makes fat cells act like they're infected
(Medical Xpress)—The inflammation of fat tissue is part of a spiraling series of events that leads to the development of type 2 diabetes in some obese people. But researchers have not understood what triggers ...
Medical research
Mar 05, 2013 |
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Discovery of human genetic mutation could lead to new treatments for type 1 diabetes
In type 1 diabetes, the immune system destroys insulin-producing cells in the pancreas, but the precise cause has not been clear. A study published by Cell Press on March 5th in Cell Metabolism reveals that a ...
Genetics
Mar 05, 2013 |
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Recon 2 modeling may help tailor treatments for patients with metabolic diseases, cancer
An international team of researchers, including an investigator with the Virginia Bioinformatics Institute at Virginia Tech, has produced what may be the most comprehensive computer model of human metabolism yet developed.
Medical research
Mar 04, 2013 |
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International consortium builds 'Google Map' of human metabolism
Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction ...
Medical research
Mar 03, 2013 |
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Proteins with mutations in 'prion-like' segments considered candidates for inherited forms of ALS
A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders. James Shorter, Ph.D., assistant professor of Biochemistry and Biophysics at the Perelman ...
Medical research
Mar 03, 2013 |
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Study maps human metabolism in health and disease
Scientists have produced an instruction manual for the human genome that provides a framework to better understand the relationship between an individual's genetic make-up and their lifestyle.
Genetics
Mar 03, 2013 |
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AAD: Skin changes can be first sign of underlying condition
(HealthDay)—Skin changes, including new rash, new growths, discoloration, and changes in texture, could be among the first signs indicating an underlying medical condition, according to information presented ...
Diseases, Conditions, Syndromes
Mar 01, 2013 |
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New Zealand faces wave of diabetes, research suggests
Nearly one fifth of New Zealand's adult population face the very real spectre of living with diabetes, according to new University of Otago research published in the New Zealand Medical Journal today.
Diabetes
Mar 01, 2013 |
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Study shows key enzyme missing from aggressive form of breast cancer
A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain—providing insight ...
Cancer
Feb 28, 2013 |
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Eating junk food while pregnant may make your child a junk food addict
Here's another reason why a healthy diet during pregnancy is critical to the future health of your children: New research published in the March 2013 issue of The FASEB Journal, suggests that pregnant mothers who consume junk f ...
Health
Feb 28, 2013 |
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Lipid researcher, 98, reports on the dietary causes of heart disease
A 98-year-old researcher argues that, contrary to decades of clinical assumptions and advice to patients, dietary cholesterol is good for your heart – unless that cholesterol is unnaturally oxidized (by ...
Cardiology
Feb 27, 2013 |
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