Adding intestinal enzyme to diets of mice appears to prevent, treat metabolic syndrome
Feeding an intestinal enzyme to mice kept on a high-fat diet appears to prevent the development of metabolic syndrome – a group of symptoms associated with type 2 diabetes, cardiovascular disease and fatty liver – and ...
Medical research
Apr 08, 2013 |
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Mitochondrial metabolic regulator SIRT4 guards against DNA damage
(Medical Xpress)—Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.
Cancer
Apr 05, 2013 |
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Gut microbes at root of severe malnutrition in kids
A study of young twins in Malawi, in sub-Saharan Africa, finds that bacteria living in the intestine are an underlying cause of a form of severe acute childhood malnutrition.
Medical research
Jan 30, 2013 |
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BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
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When timing is everything: Research says beneficial mutations need specific circumstances to win out
When it comes to the sort of beneficial mutations that drive natural selection, there's new evidence that, evolutionarily speaking, timing is everything.
Genetics
Mar 20, 2013 |
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Study reveals how diabetes drug delays ageing in worms
A widely prescribed type 2 diabetes drug slows down the ageing process by mimicking the effects of dieting, according to a study published today using worms to investigate how the drug works.
Medical research
Mar 28, 2013 |
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Scientists find potential loophole in pancreatic cancer defenses
Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control ...
Cancer
Mar 27, 2013 |
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Treatment by naturopathic doctors shows reduction in cardiovascular risk factors
Counselling and treatment with naturopathic care as well as enhanced usual care reduced the prevalence of metabolic syndrome, a risk factor for heart disease, by 17% over a year for participants in a randomized controlled ...
Cardiology
Apr 29, 2013 |
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Circadian rhythms can be modified for potential treatment of disorders
(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Cardiology
Jan 22, 2013 |
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Gene variants link to insulin resistance based on diet
(HealthDay)—Variants of insulin receptor substrate 1 (IRS1) are associated with insulin resistance and metabolic syndrome, but only under particular dietary conditions, according to a study published online ...
Diabetes
Apr 28, 2013 |
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Genes and obesity: Fast food isn't only culprit in expanding waistlines—DNA is also to blame
Researchers at UCLA say it's not just what you eat that makes those pants tighter—it's also genetics. In a new study, scientists discovered that body-fat responses to a typical fast-food diet are determined in large part ...
Medical research
Jan 08, 2013 |
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A scanner for hereditary defects
Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. ...
Genetics
Jan 24, 2013 |
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Simulated Mars mission reveals body's sodium rhythms
Clinical pharmacologist Jens Titze, M.D., knew he had a one-of-a-kind scientific opportunity: the Russians were going to simulate a flight to Mars, and he was invited to study the participating cosmonauts.
Medical research
Jan 08, 2013 |
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Cooling may prevent trauma-induced epilepsy
(Medical Xpress)—In the weeks, months and years after a severe head injury, patients often experience epileptic seizures that are difficult to control. A new study in rats suggests that gently cooling the ...
Neuroscience
Feb 21, 2013 |
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Researchers identify new target for common heart condition
Researchers have found new evidence that metabolic stress can increase the onset of atrial arrhythmias, such as atrial fibrillation (AF), a common heart condition that causes an irregular and often abnormally fast heart rate. ...
Cardiology
Jan 08, 2013 |
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