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Insight into the dazzling impact of insulin in cells

Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.

Medical research created May 21, 2013 | popularity 4.6 / 5 (8) | comments 0 | with audio podcast

Defective cellular waste removal explains why Gaucher patients often develop Parkinson's disease

Gaucher disease causes debilitating and sometimes fatal neurodegeneration in early childhood. Recent studies have uncovered a link between the mutations responsible for Gaucher disease and an increased risk ...

Parkinson's & Movement disorders created 11 hours ago | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists uncover molecular roots of cocaine addiction in the brain

Researchers at Johns Hopkins have unraveled the molecular foundations of cocaine's effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice. The compound, already proven safe ...

Neuroscience created May 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

Research uncovers a potential role of two proteins in diabetes

(Medical Xpress)—Flinders University researchers are breaking new ground in a decade-long journey to pinpoint the function of two closely related proteins.

Diabetes created May 20, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Treatment of sleep apnea improves glucose levels in prediabetes

Optimal treatment of sleep apnea in patients with prediabetes improves blood sugar (glucose) levels and thus can reduce cardiometabolic risk, according to a study to be presented at the ATS 2013 International Conference in ...

Sleep apnea created May 20, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study finds that sleep apnea and Alzheimer's are linked

A new study looking at sleep-disordered breathing (SDB) and markers for Alzheimer's disease (AD) risk in cerebrospinal fluid (CSF) and neuroimaging adds to the growing body of research linking the two.

Alzheimer's disease & dementia created May 19, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Individual and small-chain restaurant meals exceed recommended daily calorie needs, study shows

As the restaurant industry prepares to implement new rules requiring chains with 20 or more locations to post calorie content information, the results of a new study suggest that it would be beneficial to public health for ...

Health created May 13, 2013 | popularity not rated yet | comments 0 | with audio podcast

Nerve stimulation for severe depression changes brain function

For nearly a decade, doctors have used an implanted electronic stimulator to treat severe depression in people who don't respond to standard antidepressant therapy.

Psychology & Psychiatry created May 07, 2013 | popularity not rated yet | comments 0 | with audio podcast

Discovery of new hormone opens doors to new type 2 diabetes treatments

Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in ...

Diabetes created May 07, 2013 | popularity 4.6 / 5 (8) | comments 1 | with audio podcast

Type 1 diabetes and heart disease linked by inflammatory protein

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...

Inflammatory disorders created May 07, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Researchers discover endogenous antibiotic in the brain

Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid. ...

Medical research created May 06, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Research suggests link between elevated blood sugar, Alzheimer's risk

(Medical Xpress)—A new University of Arizona study, published in the journal Neurology, suggests a possible link between elevated blood sugar levels and risk for developing Alzheimer's disease.

Alzheimer's disease & dementia created May 06, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study uncovers mechanism for how grapes reduce heart failure associated with hypertension

A study appearing in the Journal of Nutritional Biochemistry demonstrates that grapes are able to reduce heart failure associated with chronic high blood pressure (hypertension) by increasing the activity of several genes ...

Cardiology created May 02, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Study identifies genes, pathways altered during relaxation response practice

A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) finds that elicitation of the relaxation response ...

Psychology & Psychiatry created May 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Brain region may hold key to aging

While the search continues for the Fountain of Youth, researchers may have found the body's "fountain of aging": the brain region known as the hypothalamus. For the first time, scientists at Albert Einstein ...

Neuroscience created May 01, 2013 | popularity 4.8 / 5 (21) | comments 8 | with audio podcast

Metabolism

Metabolism is the set of chemical reactions that occur in living organisms to maintain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments. Metabolism is usually divided into two categories. Catabolism breaks down organic matter, for example to harvest energy in cellular respiration. Anabolism, on the other hand, uses energy to construct components of cells such as proteins and nucleic acids.

The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed into another by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable but thermodynamically unfavorable reactions by coupling them to favorable ones, and because they act as catalysts to allow these reactions to proceed quickly and efficiently. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or signals from other cells.

The metabolism of an organism determines which substances it will find nutritious and which it will find poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, also influences how much food an organism will require.

A striking feature of metabolism is the similarity of the basic metabolic pathways between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all organisms, being found in species as diverse as the unicellular bacteria Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolism are most likely the result of the high efficiency of these pathways, and of their early appearance in evolutionary history.

For more information about Metabolism, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: genes , protein , cells , amino acids , diabetes