News tagged with metastasis

Related topics: cancer · cancer cells · breast cancer · tumor · cells

New '4-D' lung cancer model could quicken discoveries

Without good models to study cancer metastasis—the spread of cancer cells from one organ to another—cancer researchers have struggled to understand tumor progression fully, and new therapies targeting the main causes ...

Apr 15, 2015
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Golgi trafficking controlled by G proteins

A family of proteins called G proteins are a recognized component of the communication system the human body uses to sense hormones and other chemicals in the bloodstream and to send messages to cells. In work that further ...

Apr 09, 2015
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How immune cells facilitate the spread of breast cancer

The body's immune system fights disease, infections and even cancer, acting like foot soldiers to protect against invaders and dissenters. But it turns out the immune system has traitors amongst their ranks. Dr. Karin de ...

Mar 30, 2015
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Stress granules ease the way for cancer metastasis

Tumors that produce more stress granules are more likely to metastasize, according to a study published in The Journal of Cell Biology. The results suggest that drugs to inhibit the formation of these structures might rein ...

Mar 23, 2015
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Metastasis

Metastasis (Greek: displacement, μετά=next + στάσις=placement, plural: metastases), or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one organ or part to another non-adjacent organ or part. Only malignant tumor cells and infections have the established capacity to metastasize; however, this is recently reconsidered by new research.

Cancer cells can break away, leak, or spill from a primary tumor, enter lymphatic and blood vessels, circulate through the bloodstream, and settle down to grow within normal tissues elsewhere in the body. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most tumors and other neoplasms can metastasize, although in varying degrees (e.g., glioma and basal cell carcinoma rarely metastasize).

When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are like those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.

This text uses material from Wikipedia, licensed under CC BY-SA

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