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News tagged with metastasis

Race to the top: Decoding metastasis

(Medical Xpress) -- One of cancer's greatest and most insidious threats is metastasis – the three-dimensional migratory invasion of cancer cells from primary tumors to a distant part of the body. The ...

Cancer created Apr 29, 2011 | popularity 5 / 5 (12) | comments 0 | with audio podcast feature

Four new drugs will change prostate cancer care

After a decade and a half of near stagnation, four new drugs could help make advanced prostate cancer a chronic illness instead of a terminal disease, a leading Colorado prostate cancer expert says.

Cancer created Feb 16, 2012 | popularity 3.3 / 5 (13) | comments 2 | with audio podcast

Limits to growth: Scientists identify key metastasis-enabling enzyme

(Medical Xpress) -- On the complex road to eradicating cancer, controlling or preventing metastatic growth initiated by primary tumors is high on the to-do list. A key area of such research is the development ...

Medical research created May 22, 2012 | popularity 4.3 / 5 (9) | comments 0 | with audio podcast feature

New synthetic molecules treat autoimmune disease in mice

A team of Weizmann Institute scientists has turned the tables on an autoimmune disease. In such diseases, including Crohn's and rheumatoid arthritis, the immune system mistakenly attacks the body's tissues. But the scientists ...

Immunology created Dec 25, 2011 | popularity 4.8 / 5 (8) | comments 0 | with audio podcast

Scientists find gene that inhibits pancreas cancer spread

Scientists have identified a gene that slows the spread of pancreatic cancer tumours, paving the way for targeted treatment of one of the deadliest forms of the disease, said a paper published Sunday.

Cancer created Apr 29, 2012 | popularity 5 / 5 (7) | comments 0

Cancerous tumors deliver pro-metastatic information in secreted vesicles

Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called ...

Cancer created May 29, 2012 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Research breakthrough could halt melanoma metastasis

In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 ...

Cancer created Nov 14, 2012 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Lack of oxygen in cancer cells leads to growth and metastasis

(Medical Xpress)—It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, ...

Cancer created Sep 13, 2012 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Scientists discover key process that allows colon cancer to metastasize

A team of 17 researchers, led by scientists Eduard Batlle and Elena Sancho in the Colorectal Cancer Laboratory at the Institute for Research in Biomedicine (IRB Barcelona), have determined that the ability ...

Cancer created Nov 12, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Tumor-activated protein promotes cancer spread

Researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center report that cancers physically alter cells in the lymphatic system – a network of vessels that transports and ...

Cancer created May 13, 2013 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Researchers show molecule inhibits metastasis of colon, melanoma cancers

Researchers at the Medical College of Wisconsin have shown that a protein can inhibit metastasis of colon and melanoma cancers. The findings are published in the October 10, 2011 issue of Proceedings of the National Academy of ...

Cancer created Oct 10, 2011 | popularity 5 / 5 (4) | comments 1 | with audio podcast

Key driver of metastasis identified

Scientists at Dalhousie University in Nova Scotia have identified a key mechanism of metastasis that could lead to blocking tumor growth if their findings are confirmed.

Cancer created Oct 31, 2011 | popularity 5 / 5 (4) | comments 2 | with audio podcast

Uncovering a key player in metastasis

About 90 percent of cancer deaths are caused by secondary tumors, known as metastases, which spread from the original tumor site.

Cancer created Nov 15, 2011 | popularity 5 / 5 (4) | comments 1 | with audio podcast

Tension on gut muscles induces cell invasion in zebrafish intestine, mimicking cancer metastasis

The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering ...

Cancer created Sep 07, 2012 | popularity 4 / 5 (5) | comments 0 | with audio podcast

Scientists illuminate cancer cells' survival strategy

A team led by scientists at The Scripps Research Institute has discovered key elements of a strategy commonly used by tumor cells to survive when they spread to distant organs. The finding could lead to drugs that could inhibit ...

Cancer created Jan 26, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Metastasis

Metastasis (Greek: displacement, μετά=next + στάσις=placement, plural: metastases), or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one organ or part to another non-adjacent organ or part. Only malignant tumor cells and infections have the established capacity to metastasize; however, this is recently reconsidered by new research.

Cancer cells can break away, leak, or spill from a primary tumor, enter lymphatic and blood vessels, circulate through the bloodstream, and settle down to grow within normal tissues elsewhere in the body. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most tumors and other neoplasms can metastasize, although in varying degrees (e.g., glioma and basal cell carcinoma rarely metastasize).

When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are like those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.

For more information about Metastasis, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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