Mount Sinai researchers have discovered a previously unknown mechanism in which not-yet-malignant cells from early breast cancer tumors travel to other organs and, eventually, "turn on" and become metastatic breast cancer.
Apr 26, 2022
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When cancer cells break away from a primary tumor and migrate to other organs, this is called "metastatic cancer." The organs affected by these metastases, however, depend in part on their tissue of origin. In the case of ...
Apr 21, 2022
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A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and ...
Apr 19, 2022
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Mutation of a gene called ARID2 plays a role in increasing the chance that melanoma, a deadly skin cancer, will turn dangerously metastatic, Mount Sinai researchers report.
Apr 18, 2022
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Cancer cells can disrupt a metabolic pathway that breaks down fats and proteins to boost the levels of a byproduct called methylmalonic acid, thereby driving metastasis, according to research led by scientists at Weill Cornell ...
Apr 13, 2022
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New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer. Findings from the trial, ...
Apr 5, 2022
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A new therapeutic strategy for hepatocellular cancer (HCC) that initially primes the tumor with an immune checkpoint inhibitor before using a multikinase inhibitor drug showed great promise for treating patients with the ...
Mar 16, 2022
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Metastatic cells occur in many forms of cancer. They originate in primary tumors and then break away and migrate. They travel through the tissues surrounding them, through blood vessels or lymphatic channels. Along the way, ...
Mar 8, 2022
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An experimental form of immunotherapy that uses an individual's own tumor-fighting immune cells could potentially be used to treat people with metastatic breast cancer, according to results from an ongoing clinical trial ...
Feb 1, 2022
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When cancer cells metastasize, they morph, becoming missile-shaped in order to penetrate into other tissues throughout the body.
Dec 16, 2021
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