News tagged with methotrexate
Ultrasound findings can improve classification of RA
(HealthDay)—Compared to clinical diagnosis of synovitis, ultrasound-detected synovitis provides either improved sensitivity or specificity when used with the American College of Rheumatology/European League ...
Arthritis & Rheumatism
May 15, 2013 |
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First study on long-term cognitive effects of breast cancer CMF chemotherapy finds subtle impairment
Dutch investigators have reported that women who received CMF chemotherapy (a combination regimen including the drugs cyclophosphamide, methotrexate, and 5-fluorouracil) for breast cancer between 1976 and 1995 scored worse ...
Cancer
Feb 27, 2012 |
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Rheumatism drug also effective at half dose
The treatment of moderately active rheumatoid arthritis with the tumour necrosis factor inhibitor Etanercept achieves excellent success in more than 80 per cent of patients. With this method, the success ...
Arthritis & Rheumatism
Jan 18, 2013 |
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Newly approved oral medication slows rheumatoid arthritis joint damage
A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis (RA) patients who did not respond to methotrexate (MTX). Results of the 12-month ...
Arthritis & Rheumatism
Jan 24, 2013 |
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Choice of psoriasis treatment affects CVD event rates
(HealthDay)—Compared with other anti-psoriatic therapies, systemic anti-inflammatory treatment of patients with severe psoriasis with biologic agents or methotrexate is associated with a lower combined ...
Immunology
Sep 27, 2012 |
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Injection of methotrexate not superior to oral therapy in juvenile arthritis treatment
A retrospective analysis of methotrexate (MTX) safety data found that injection of this disease-modifying anti-rheumatic drug (DMARD) was not superior to oral therapy in long-term treatment of patients with juvenile idiopathic ...
Arthritis & Rheumatism
May 30, 2012 |
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FDA: New suppliers to ease 2 cancer drug shortages
Federal regulators said Tuesday that they've approved new suppliers for two crucial cancer drugs, easing critical shortages - at least for the time being - that have patients worried about missing life-saving treatments.
Medications
Feb 21, 2012 |
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Cancer drugs help the hardest cases of Pompe disease
Kids with Pompe disease fail because of a missing enzyme, GAA, that leads to dangerous sugar build-up, which affects muscles and movement. An enzyme replacement treatment pioneered at Duke University has saved many lives, ...
Genetics
Jan 05, 2012 |
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Fertility after ectopic pregnancy: Study finds reassuring evidence on different treatments
The first randomised trial to compare treatments for ectopic pregnancies has found no significant differences in subsequent fertility between medical treatment and conservative surgery on one hand, and conservative or radical ...
Obstetrics & gynaecology
Mar 12, 2013 |
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Newer, more expensive psoriasis drugs only slightly more effective than older therapies under real world conditions
More expensive biologic treatments for psoriasis were only marginally more effective than standard treatments, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. ...
Diseases, Conditions, Syndromes
Apr 30, 2012 |
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Methotrexate use linked to reduced mortality in RA
(HealthDay)—Use of methotrexate for one year or more is associated with a reduction in the risk of mortality for patients with rheumatoid arthritis (RA), according to a study published online Oct. 8 in ...
Arthritis & Rheumatism
Oct 14, 2012 |
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Women whose first pregnancy was ectopic have fewer children
Women whose first pregnancy is ectopic are likely to have fewer children in the following 20-30 years than women whose first pregnancy ends in a delivery, miscarriage or abortion, according to results from a study of nearly ...
Obstetrics & gynaecology
Oct 17, 2012 |
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UVB preferred for treatment of moderate to severe psoriasis
(HealthDay) -- Ultraviolet B (UVB) is preferred by dermatologists for first-line treatment of moderate to severe psoriasis in both healthy male and female patients, according to a study published in the March ...
Diseases, Conditions, Syndromes
Feb 24, 2012 |
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Xeljanz approved for rheumatoid arthritis
(HealthDay)—Xeljanz (tofacitinib) has been approved by the U.S. Food and Drug Administration to treat symptoms of rheumatoid arthritis (RA) among people who can't tolerate, or haven't been helped by, the drug methotrexate.
Arthritis & Rheumatism
Nov 07, 2012 |
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Bortezomib beneficial in graft-versus-host disease prophylaxis
(HealthDay) -- Patients with hematologic malignancies undergoing an HLA-mismatched unrelated donor (MMUD) reduced-intensity conditioning (RIC) hematopoietic stem cell transplantation (HSCT) may benefit from ...
Cancer
Aug 08, 2012 |
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Methotrexate
Methotrexate (rINN) ( /mɛθɵˈtrɛkseɪt/), abbreviated MTX and formerly known as amethopterin, is an antimetabolite and antifolate drug. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid. Methotrexate began to replace the more toxic antifolate aminopterin starting in the 1950s. The drug was developed by Yellapragada Subbarao.
For more information about Methotrexate, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
