News tagged with methotrexate
First study on long-term cognitive effects of breast cancer CMF chemotherapy finds subtle impairment
Dutch investigators have reported that women who received CMF chemotherapy (a combination regimen including the drugs cyclophosphamide, methotrexate, and 5-fluorouracil) for breast cancer between 1976 and 1995 scored worse ...
Cancer
Feb 27, 2012 |
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Study compares effectiveness of psoriasis treatments
(HealthDay) -- The effectiveness of therapies for psoriasis is variable, and may be lower in real-world settings than in trial settings, according to a study published in the April issue of the Archives of ...
Diseases, Conditions, Syndromes
Apr 20, 2012 |
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Newer, more expensive psoriasis drugs only slightly more effective than older therapies under real world conditions
More expensive biologic treatments for psoriasis were only marginally more effective than standard treatments, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. ...
Diseases, Conditions, Syndromes
Apr 30, 2012 |
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Tocilizumab is more effective than adalimumab at reducing signs and symptoms of rheumatoid arthritis
Data presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, demonstrates that tocilizumab monotherapy is more effective than adalimumab monotherapy in the treatment of rheumatoid arthritis ...
Arthritis & Rheumatism
Jun 06, 2012 |
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Researchers test drug combinations to prevent graft vs. host disease
Researchers at Moffitt Cancer Center have conducted a clinical trial aimed at preventing graft vs. host disease (GVHD) in patients who have received hematopoietic (blood) cell transplants (HCT). The study, comparing the drug ...
Diseases, Conditions, Syndromes
Jun 26, 2012 |
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Newly approved oral medication slows rheumatoid arthritis joint damage
A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis (RA) patients who did not respond to methotrexate (MTX). Results of the 12-month ...
Arthritis & Rheumatism
Jan 24, 2013 |
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5 Questions: Link on recent shortages in cancer-drug supply
In February, the United States came within weeks of running out of preservative-free methotrexate, a generic drug that is an essential component of chemotherapy treatments for the most common childhood cancer, acute lymphoblastic ...
Medications
Apr 24, 2012 |
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Methotrexate
Methotrexate (rINN) ( /mɛθɵˈtrɛkseɪt/), abbreviated MTX and formerly known as amethopterin, is an antimetabolite and antifolate drug. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid. Methotrexate began to replace the more toxic antifolate aminopterin starting in the 1950s. The drug was developed by Yellapragada Subbarao.
For more information about Methotrexate, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
