News tagged with microenvironment
Researchers develop sperm-sorting design that may aid couples undergoing in vitro fertilization
(Medical Xpress)—According to the World Health Organization, approximately 70 million couples experience infertility worldwide. Current data suggests that nearly one third of infertility disorders are due ...
Medical research
May 23, 2013 |
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Changing cancer's environment to halt its spread
By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces ...
Cancer
May 21, 2013 |
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Scientists define a new mechanism leading to tumor hypoxia
An article published recently in Tumor Microenvironment and Therapy - an open access journal by Versita, defines a novel mechanism of tumor hypoxia induced by the longitudinal gradient of residual oxygen along tumor vessel ...
Cancer
May 09, 2013 |
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How some cancers 'poison the soil' to block metastasis
Cancer spread or metastasis can strike unprecedented fear in the minds of cancer patients. The "seed and the soil" hypothesis proposed by Stephen Paget in 1889 is now widely accepted to explain how cancer cells (seeds) are ...
Cancer
Apr 30, 2013 |
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Storming the gates: Study probes how pancreatic cancers metastasize
Researchers at the University of North Carolina at Chapel Hill have discovered that a protein found in the cells surrounding pancreatic cancers play a role in the spread of the disease to other parts of the ...
Cancer
Mar 25, 2013 |
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No genetic clock for neuron longevity
(Medical Xpress)—People are living longer than ever before, thanks to medical and technological advances. Unfortunately, aging can be associated with a decrease in brain function. This is because, unlike ...
Neuroscience
Feb 27, 2013 |
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Impact of stem cell transplantation location in brain a crucial factor for cell survival
Researchers at the Johns Hopkins University in Baltimore, Md., and the Mossakowski Medical Research Centre in Warsaw, Poland, have found that nonself-donated cells (allografts) better survive implantation into the brains ...
Medical research
Feb 13, 2013 |
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Key molecule suppresses growth of cancerous liver tumors, study finds
(Medical Xpress)—A molecule already implicated in a number of diverse cellular functions can suppress the growth of tumors in the liver, a Mayo Clinic Cancer Center study has found. Its name is IQGAP1, and when the molecule ...
Cancer
Feb 13, 2013 |
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Diabetes distresses bone marrow stem cells by damaging their microenvironment
New research has shown the presence of a disease affecting small blood vessels, known as microangiopathy, in the bone marrow of diabetic patients. While it is well known that microangiopathy is the cause of renal damage, ...
Diabetes
Jan 31, 2013 |
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Tumor cells engineer acidity to drive cell invasion
Researchers at Moffitt Cancer Center and colleagues at Wayne State University School of Medicine investigated the acidity in solid tumors to determine if pH levels play a role in cancer cell invasion in surrounding tissues. ...
Cancer
Jan 25, 2013 |
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Researchers prevent cancer spread by blocking tissue scarring
What to fear most if faced by a cancer diagnosis is the spread of the cancer to other parts of the body. This process called metastasis accounts for over 90% of cancer patient deaths and therefore is a strong focus for cancer ...
Cancer
Jan 24, 2013 |
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Researchers develop novel 3-D culture system for inflammatory breast cancer
Inflammatory breast cancer (IBC) is a very rare and aggressive disease that progresses rapidly and is associated with a very low survival rate. To understand how this type of cancer spreads, it's crucial to characterize the ...
Cancer
Dec 09, 2012 |
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Scientists discover key process that allows colon cancer to metastasize
A team of 17 researchers, led by scientists Eduard Batlle and Elena Sancho in the Colorectal Cancer Laboratory at the Institute for Research in Biomedicine (IRB Barcelona), have determined that the ability ...
Cancer
Nov 12, 2012 |
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Discovery reveals important clues to cancer metastasis
In recent years investigators have discovered that breast tumors are influenced by more than just the cancer cells within them. A variety of noncancerous cells, which in many cases constitute the majority ...
Cancer
Oct 11, 2012 |
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Ovarian cancer stem cells targeted in new research
Ovarian cancer takes the lives of nearly 900 Australian women each year. It's called the silent killer because by the time most cases are detected, the cancer has spread to other vital organs throughout the abdominal area.
Cancer
Oct 05, 2012 |
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