Knocking out part of the innate immune system to improve cancer therapy
Researchers at Shanghai Jiao Tong University School of Medicine, China, have discovered that shutting down part of the innate immune system increases anti-tumor activity.
Researchers at Shanghai Jiao Tong University School of Medicine, China, have discovered that shutting down part of the innate immune system increases anti-tumor activity.
The cells that make up our bodies are constantly communicating with each other, sometimes directly by physical touch. These interactions allow cells to respond to their neighbors, adapt to their surrounding environment and ...
Nov 16, 2023
0
115
Anticancer treatment strategies increasingly seek to raise reactive oxygen species (ROS) levels, cause macromolecular damage, and kill cancer cells. Electromagnetic fields can elevate intracellular reactive oxygen species ...
A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment ...
Nov 9, 2023
0
28
New research from scientists at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) determined that a particular gene—MDA-9/Syntenin-1/SDCBP—is the ringleader behind a molecular domino ...
Nov 6, 2023
0
20
Scientists have recently concluded a preclinical study that highlights the potential of SIWA318H, an advanced glycation end product (AGE)-targeting antibody, in the fight against pancreatic cancer. The results are published ...
Oct 27, 2023
0
44
Glioblastoma (GBM), an aggressive brain cancer, is notoriously resistant to treatment, with recurrent GBM associated with survival of less than 10 months. Immunotherapies, which mobilize the body's immune defenses against ...
Oct 18, 2023
0
344
Glioblastoma is the most common type of brain tumor that affects adults and, unfortunately, still remains incurable. In a new study, researchers have demonstrated that a specific mitochondrial protein plays an important role ...
Oct 17, 2023
0
0
A molecular signature that predicts aggressive thyroid cancer could help guide treatment approaches for patients, according to a study published in the journal Cell Genomics.
Sep 29, 2023
0
67
Loss of the "housekeeping" gene methylthioadenosine phosphorylase, or MTAP, is a common event in cancer. Patients with melanoma or bladder cancer whose tumor cells lack a functioning version of the gene tend not to respond ...
Sep 28, 2023
0
0