Scientists from the University of California, Irvine School of Biological Sciences have discovered how to forestall Alzheimer's disease in a laboratory setting, a finding that could one day help in devising targeted drugs ...
Aug 21, 2019
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552
Examining post-mortem tissue from the brains of people with Alzheimer's disease, Stanford University School of Medicine investigators identified what appear to be iron-containing microglia—specialized scavenger cells that ...
Jul 20, 2015
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40
People with a variant copy of the TREM2 gene have an increased risk of developing Alzheimer's disease, but researchers are only beginning to understand why.
Jul 20, 2016
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350
A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the central nervous system—including the retina of the eye—serve as "gatekeepers," or biosensors and facilitators, of ...
Apr 22, 2019
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299
Sanford Burnham Prebys Medical Research Institute (SBP) researchers have published two new studies in Neuron that describe how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins ...
Mar 7, 2018
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260
A team of researchers working at McGill University has found that activation of microglia in the spinal cord following a nerve injury can lead to an increased sensitivity to pain. In their paper published in the journal Science, ...
Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid ...
Jun 7, 2022
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312
Excessive weight around our middle gives our brain's resident immune cells heavy exposure to a signal that turns them against us, setting in motion a crescendo of inflammation that damages cognition, scientists say.
Mar 3, 2020
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398
In preclinical studies, Mayo Clinic scientists and collaborators have identified the molecular mechanism used by the brain's "cleaners" as they remove a problematic protein in the brain. This work, published in Nature Neuroscience, ...
Jan 4, 2022
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289
Supplementing the body's short chain fatty acids can improve stroke recovery, according to research in mice recently published in JNeurosci. Short chain fatty acid supplementation may be a non-invasive addition to stroke ...
Jan 2, 2020
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403
