Oncology & Cancer

Membrane around tumors may be key to preventing metastasis

For cancer cells to metastasize, they must first break free of a tumor's own defenses. Most tumors are sheathed in a protective "basement" membrane—a thin, pliable film that holds cancer cells in place as they grow and ...

Neuroscience

Physical principles for scalable neural recording

(Medical Xpress)—It took nearly two months, but the videos from the May 6th-7th national BRAIN Initiative meeting are now available online. Although the title of that workshop made central mention of the idea Physical and ...

Neuroscience

Structural dynamics underlying memory in aging brains

(Medical Xpress)—When the brains of those who have succumbed to age-related neurodegeneration are analyzed post-mortem, they typically show significant atrophy on all scales. Not only is the cortex thinner and sparser, ...

Neuroscience

New synapse type discovered through spatial proteomics

Researchers have developed a new super-resolution high-throughput imaging method. Using the new technique, the scientists were able to create a 3D neuronal cell atlas with single-molecule resolution and discovered a previously ...

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Microscopy

Microscopy is the technical field of using microscopes to view samples or objects. There are three well-known branches of microscopy, optical, electron and scanning probe microscopy.

Optical and electron microscopy involve the diffraction, reflection, or refraction of electromagnetic radiation/electron beam interacting with the subject of study, and the subsequent collection of this scattered radiation in order to build up an image. This process may be carried out by wide-field irradiation of the sample (for example standard light microscopy and transmission electron microscopy) or by scanning of a fine beam over the sample (for example confocal laser scanning microscopy and scanning electron microscopy). Scanning probe microscopy involves the interaction of a scanning probe with the surface or object of interest. The development of microscopy revolutionized biology and remains an essential tool in that science, along with many others including materials science and numerous engineering disciplines.

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