Northwestern Medicine scientists have uncovered a new mechanism by which mutations in a gene parkin contribute to familial forms of Parkinson's disease. The discovery opens a new avenue for Parkinson's therapeutics, scientists ...
Jul 19, 2023
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A new research study at the Institute of Molecular Biology and Biotechnology (IMBB) of the Foundation for Research and Technology-Hellas (FORTH), published today in The EMBO Journal, reveals an intricate mechanism that impacts ...
Jul 13, 2023
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All cells have their own power plants, called mitochondria. There are often more than 100 mitochondria per cell and each possesses their own genome, which in turn contains genes responsible for energy production. If errors ...
Jul 5, 2023
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While mitochondria play a crucial role in producing the energy our cells need to carry out their various functions, when damaged, they can have profound effects on cellular function and contribute to the development of various ...
Jun 27, 2023
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Glioblastoma cancer cells use mitochondria from the central nervous system to grow and form more aggressive tumors, according to new Cleveland Clinic-led findings published in Nature Cancer.
May 11, 2023
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Scientists at the University of Liverpool have figured out how mutations in a gene called FBXL4 can lead to an excess of mitophagy—the disposal of mitochondria, the 'power stations' within nearly all human cells.
May 4, 2023
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In addition to their role in energy metabolism, mitochondria play important roles in other cellular processes, such as apoptosis, calcium signaling and the synthesis of certain biomolecules. Mitochondria have also been implicated ...
May 1, 2023
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Researchers at Nagoya University in Japan have discovered a receptor, sigma-1 receptor, and a protein, ATAD3A, that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. Since there ...
Apr 26, 2023
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Fuchs' endothelial corneal dystrophy, a degenerative eye disease, causes progressive vision loss that can induce blindness. It is the leading cause of corneal transplantation, but the scarcity of grafts hinders its treatment. ...
Apr 14, 2023
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Brains are like puzzles, requiring many nested and co-dependent pieces to function well. The brain is divided into areas, each containing many millions of neurons connected across thousands of synapses. These synapses, which ...
Apr 12, 2023
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