Researchers at the Broad Institute of MIT and Harvard, Cambridge, have interrogated several interconnected questions related to mitochondrial DNA (mtDNA) heteroplasmy and the influence of nuclear genetics.
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined into narrow neuritic ...
Researchers at the UCLA stem cell center and the departments of chemistry and biochemistry and pathology and laboratory medicine have identified, for the first time, a generic way to correct mutations in human mitochondrial ...
Mar 12, 2012
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The survival of neurons, unlike most other cells in the body, depends largely on the energy provided by mitochondria, intracellular organelles that contain their DNA to function properly.
Mar 25, 2024
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Myotonic dystrophy 2 (DM2) is a form of muscular dystrophy, a disease that leads to progressive muscle degeneration. It is caused by the expansion of a repetitive DNA sequence containing multiple CCTG bases in the CNBP gene. ...
Feb 21, 2024
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VUB professor Claudia Spits, of the Vrije Universiteit Brussel Reproduction and Genetics research group, has identified a genetic cause for the increased risk of low birth weight in babies born following assisted reproductive ...
Feb 12, 2024
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The human brain is an organ that requires 20% to 25% of the energy the body creates. This high energy demand for neuronal functions depends on the transport and precise distribution of mitochondria—the energy-generating ...
Feb 7, 2024
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In a first, Tel Aviv University researchers have discovered that the production and regulation of mitochondrial organelles in the brain's nerve cells (neurons) becomes significantly impaired with the deletion of a gene called ...
Jan 10, 2024
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A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis ...
Jan 2, 2024
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Major depressive disorder affects 16.1 million adults in the United States and costs $210 billion annually. While the primary symptoms of depression are psychological, scientists and doctors have come to understand that depression ...
Dec 15, 2023
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