Many of the characteristics that make people so different from each other are often the result of small differences in the DNA between individuals. Variation in just a single base in our DNA can cause significant variation ...
Dec 9, 2019
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Mitochondrial donation is an assisted reproductive technology sometimes described as "three-parent IVF". It's designed for women at high risk of passing on faulty mitochondrial DNA and having a child with severe mitochondrial ...
Nov 11, 2019
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Disturbances in the function of mitochondrial DNA can accelerate the ageing process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism. Offering a new perspective ...
Oct 8, 2019
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A pair of collaborative studies led by Fen-Biao Gao, Ph.D., have identified two potential drug targets for the diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The studies, which appear in Nature ...
May 15, 2019
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Diseases affecting mitochondria, the powerhouses of cells, are often caused by mutations in the mitochondrial DNA. Symptoms of such mitochondrial diseases in mice can be ameliorated by increasing their levels of mitochondrial ...
Apr 4, 2019
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For more than two decades, mutations in a gene located in the DNA of mitochondria have been classified as a mitochondrial disease and linked to a particular set of symptoms. However, according to new findings from researchers ...
Mar 12, 2019
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Sepsis is a life-threatening systemic inflammatory condition that develops in response to infection. One of its major complications is cardiovascular dysfunction, in which deterioration of the heart muscle, driven by decreased ...
Jan 22, 2019
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A team of researchers from the U.S., China and Taiwan has found some rare instances of fathers passing mitochondrial DNA (mtDNA) to their offspring. In their paper published in Proceedings of the National Academy of Sciences, ...
About 1.5 billion years ago, tiny visitors came to live inside the cells that later evolved into all plant and animal life—including humans.
Nov 7, 2018
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Researchers have developed a genome editing tool for the potential treatment of mitochondrial diseases: serious and often fatal conditions which affect 1 in 5,000 people.
Sep 24, 2018
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