Neuroscience

New therapeutic strategies for spinal muscular atrophy

Modulating the activity of a kinase in motor neurons may help mitigate mitochondrial defects and other symptoms of spinal muscular atrophy, offering a new therapeutic avenue for the devastating disease, according to a Northwestern ...

Medical research

Study reveals importance of gene MOF in skin development

Northwestern Medicine scientists have revealed how a gene considered essential for histone modification regulates skin development, according to a recent study published in Nature Communications.

Psychology & Psychiatry

Abnormal 12-hour cyclic gene activity found in schizophrenic brains

Researchers at the University of Pittsburgh School of Medicine, U.S. present the first evidence of 12-hour cycles of gene activity in the human brain. Published in the open access journal PLOS Biology on January 24, the study ...

Genetics

Newly discovered protein connected to Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, ...

Health

Eight ways chemical pollutants harm the body

A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...

Medical research

New findings help explain how COVID-19 overpowers the immune system

Seeking to understand why COVID-19 is able to suppress the body's immune response, new research from the USC Leonard Davis School of Gerontology suggests that mitochondria are one of the first lines of defense against COVID-19 ...

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