News tagged with model system

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Study finds interferon, one of the body's proteins, induces persistent viral infection

Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C.

Medical research created Apr 11, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers develop new system to study trigger of cell death in nervous system

(Medical Xpress)—Researchers at the University of Arkansas have developed a new model system to study a receptor protein that controls cell death in both humans and fruit flies, a discovery that could lead to a better understanding ...

Medical research created Apr 03, 2013 | popularity 5 / 5 (1) | comments 0

Team discovers how cells distinguish friend from foe

(Medical Xpress)—Researchers at UC Davis have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes. Like burglars entering a house, hostile bacteria give themselves away by ...

Immunology created Apr 01, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Study finds immunity protein that ramps up inflammation, and agents that can block it

Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival ...

Immunology created Mar 31, 2013 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Innate immune system can kill HIV when a viral gene is deactivated

Human cells have an intrinsic capacity to destroy HIV. However, the virus has evolved to contain a gene that blocks this ability. When this gene is removed from the virus, the innate human immune system destroys HIV by mutating ...

HIV & AIDS created Mar 28, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists tie dietary influences to changes in gene expression and physiology

Sometimes you just can't resist a tiny piece of chocolate cake. Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research by scientists at the University of Massachusetts ...

Medical research created Mar 28, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Insights obtained by profiling immune response to repeat viral infections could assist vaccine design efforts

Patients who successfully beat infection with dengue virus remain vulnerable to reinfection by other dengue variants, and these secondary infections tend to be more severe. The antibodies arising from the ...

Immunology created Mar 27, 2013 | popularity 5 / 5 (1) | comments 0

New model predicts hospital readmission risk

Hospital readmissions are a costly problem for patients and for the United States health care system with studies showing nearly 20 percent of Medicare patients are readmitted to the hospital within 30 days ...

Health created Mar 25, 2013 | popularity not rated yet | comments 0

Exploring the cause of sudden unexplained death in epilepsy

Dravet syndrome (DS) is a form of infantile-onset, treatment-resistant epilepsy that is caused by a mutation in the gene encoding a voltage-gated sodium channel, SCN1A. DS patients have a 30-fold increased risk of dying from ...

Medical research created Mar 25, 2013 | popularity not rated yet | comments 0

Lymphatic vasculature: A cholesterol removal system

Reverse cholesterol transport is a process in which accumulated cholesterol is removed from tissues, including the artery wall, and transported back to the liver for excretion. Little is known about how cholesterol is removed ...

Medical research created Mar 25, 2013 | popularity not rated yet | comments 1

Protein implicated in lupus promotes disease progression by distinct mechanisms in different immune cells

Patients with systemic lupus erythematosus (SLE) come under attack by their immune system, producing 'autoantibodies' that inflict damage throughout the body. Antibodies normally target foreign proteins, ...

Immunology created Mar 13, 2013 | popularity not rated yet | comments 0

What impact does a day of roller derby have on our skin microbiome?

The human skin is home to countless microorganisms that we can't see, but these microbes help define who we are. Our invisible passengers – known as the skin microbiome - contribute to our health in numerous ways including ...

Other created Mar 12, 2013 | popularity not rated yet | comments 0

A nanogel-based treatment for lupus

Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, ...

Diseases, Conditions, Syndromes created Mar 01, 2013 | popularity not rated yet | comments 0

Drug delivery strategy eliminates myotonia symptoms in mice with myotonic dystrophy

By targeting the specific mutation that causes the hereditary neuromuscular disease myotonic dystrophy, it is possible to neutralize the mutant RNA toxicity and minimize or even eliminate the disabling symptoms ...

Diseases, Conditions, Syndromes created Feb 22, 2013 | popularity 5 / 5 (1) | comments 0

Cancer drug a possible treatment for multiple sclerosis

(Medical Xpress)—A drug that is currently used for cancer can relieve and slow down the progression of the autoimmune disease multiple sclerosis (MS) in rats, according to a new study published in PLOS ONE. The discovery, which ...

Medical research created Feb 21, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast