News tagged with model

New drug blocks gene driving cancer growth

When active, the protein called Ral can drive tumor growth and metastasis in several human cancers including pancreatic, prostate, lung, colon and bladder. Unfortunately, drugs that block its activity are ...

Sep 14, 2014
popularity 4.2 / 5 (25) | comments 2

Notch1 and osteoblasts play role in bone cancer initiation

(Medical Xpress)—A new mouse model of osteogenic sarcoma, a potentially deadly form of bone cancer, shows that high levels of Notch1, a gene that helps determine cell fate, can drive osteoblasts (cells that normally lead ...

Sep 08, 2014
popularity 5 / 5 (3) | comments 0

Intestinal barrier damage in multiple sclerosis

The present study investigates whether the function of the intestines is also attacked in MS. The results, obtained from a disease model of MS in mice, shows inflammation and changes in the barrier function of the intestines ...

Sep 04, 2014
popularity 5 / 5 (2) | comments 1

Using computers to design drugs

Designing a new medicine is an expensive and time consuming business. Typically it takes around $2 billion and ten years for a new drug to move from its initial design in the lab, to the clinic. All the ...

Aug 22, 2014
popularity 5 / 5 (6) | comments 0