News tagged with molecular cancer therapeutics


Peptides for the treatment of severe diseases

A new class of drugs for the treatment of severe diseases such as cancer and autoimmune diseases is developed by the start-up Bicycle Therapeutics. The company is generating bicyclic peptides that can selectively ...

Medical research created Apr 15, 2013 | popularity 5 / 5 (1) | comments 0

Naturally occurring substance proves effective against deadly skin cancer in laboratory tests

For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin ...

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

Study identifies growth factor essential to the most common malignant pediatric brain tumor

A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...

Cancer created Feb 28, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers identify new strategy for interfering with potent cancer-causing gene

Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...

Cancer created Feb 11, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New target for treating wide spectrum of cancers

(Medical Xpress)—UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment ...

Cancer created Jan 31, 2013 | popularity not rated yet | comments 0 | with audio podcast

Fak inhibitor proves effective against brain tumors in preclinical studies, study shows

(Medical Xpress)—Researchers from Roswell Park Cancer Institute (RPCI) have published findings from a preclinical study assessing the effectiveness of a small-molecule inhibitor, CFAK-Y15, in treating some brain cancers. ...

Cancer created Dec 24, 2012 | popularity not rated yet | comments 0

TGen-US Oncology data guides treatment of metastatic triple-negative breast cancer patients

Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) ...

Cancer created Dec 06, 2012 | popularity 5 / 5 (1) | comments 0

A study of fruit fly genes reveals how molecules cooperate to induce tumor formation

Cancer biologists have known for decades that even the most potent cancer-causing genes do not act alone. Yet, identifying which combinations of genetic changes can cause a tumor to form and disease to progress ...

Genetics created Dec 05, 2012 | popularity 5 / 5 (1) | comments 0

American Society of Clinical Oncology issues annual report on state of clinical cancer science

The American Society of Clinical Oncology (ASCO) has just released its annual report on the top cancer advances of the year. Clinical Cancer Advances 2012: ASCO's Annual Report on Progress Against Cancer, highlights major ...

Cancer created Dec 03, 2012 | popularity not rated yet | comments 0

MicroRNA makes triple-negative breast cancer homesick

Epithelial cells are homebodies – they like to attach to things and becoming detached initiates a form of cell suicide known as anoikis (literally "homeless" in Latin). But in order for cancer cells to metastasize they ...

Cancer created Nov 21, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Molecular 'portraits' of tumours match patients with trials in everyday clinical practice

Researchers in France are taking advantage of the progress in genetic and molecular profiling to analyse the make-up of individual cancer patients' tumours and, using this information, assign them to particular treatments ...

Cancer created Nov 08, 2012 | popularity 5 / 5 (1) | comments 0

First trial in humans of 'minicells': A completely new way of delivering anti-cancer drugs

A completely new way of delivering anti-cancer drugs to tumours, using 'minicells' derived from bacteria, has been tested for the first time in humans and found to be safe, well-tolerated and even induced stable disease in ...

Cancer created Nov 08, 2012 | popularity 5 / 5 (2) | comments 0

Mesothelioma drug slows disease progression in patients with an inactive NF2 gene

Preliminary findings from the first trial of a new drug for patients with mesothelioma show that it has some success in preventing the spread of the deadly disease in patients lacking an active tumour suppressor gene called ...

Cancer created Nov 08, 2012 | popularity not rated yet | comments 0

Researchers develop non-invasive technique for predicting patients' response to chemotherapy

Researchers have developed a non-invasive way of predicting how much of a cancer-killing drug is absorbed by a tumour. The preliminary study, which will be reported at the 24th EORTC-NCI-AACR Symposium on Molecular Targets ...

Cancer created Nov 07, 2012 | popularity not rated yet | comments 0

Patients with aberrations in two genes respond better to drugs blocking a well-known cancer pathway

Cancer patients with mutations or variations in two genes -– PIK3CA and PTEN -– who have failed to respond to several, standard treatments, respond significantly better to anti-cancer drugs that inhibit these genes' pathways ...

Cancer created Nov 07, 2012 | popularity not rated yet | comments 0